用于威尔逊病的葡萄糖酸锌。
Zinc gluconate for Wilson disease.
作者信息
LeDoux Mark S
机构信息
Veracity Neuroscience, Memphis, TN, USA.
University of Memphis, Memphis, TN, USA.
出版信息
Clin Park Relat Disord. 2024 Oct 5;11:100272. doi: 10.1016/j.prdoa.2024.100272. eCollection 2024.
Abstract
Due to financial constraints, a patient with Wilson disease required transitioning his maintenance pharmacotherapy from zinc acetate to zinc gluconate. Herein, we report the clinical and laboratory outcomes of this switch and review the relevant literature on the treatment of Wilson disease with zinc. Zinc gluconate can be a viable treatment option for patients with Wilson disease and may be associated with fewer gastrointestinal side effects than zinc acetate and, accordingly, improved long-term compliance and improved clinical outcomes.
摘要
由于经济限制，一名患有威尔逊病的患者需要将其维持性药物治疗从醋酸锌转换为葡萄糖酸锌。在此，我们报告了这种转换的临床和实验室结果，并回顾了有关用锌治疗威尔逊病的相关文献。葡萄糖酸锌对于威尔逊病患者可能是一种可行的治疗选择，并且与醋酸锌相比可能胃肠道副作用更少，因此长期依从性更好，临床结果也有所改善。
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Zinc Maintenance Therapy for Wilson Disease: A Comparison Between Zinc Acetate and Alternative Zinc Preparations.威尔逊病的锌维持疗法：醋酸锌与其他锌制剂的比较。
Hepatol Commun. 2019 Jul 23;3(8):1151-1158. doi: 10.1002/hep4.1384. eCollection 2019 Aug.
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