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尺骨远端巨细胞瘤的切除未重建治疗:功能结果及文献综述

Distal Ulna Giant Cell Tumor treated by Resection without Reconstruction: What were the functional outcomes and review of literature.

作者信息

Banala Tarun Reddy, Salunke Abhijeet Ashok, Bharwani Nandlal, Patel Keval, Maharjan Dipendra, Patel Shailesh, Warikoo Vikas, Sharma Mohit, Pandya Shashank

机构信息

Department of Surgical Oncology, The Gujarat Cancer and Research Institute (GCRI), Ahmedabad, Gujarat, India.

出版信息

J Orthop. 2024 Mar 6;53:118-124. doi: 10.1016/j.jor.2024.02.040. eCollection 2024 Jul.

Abstract

INTRODUCTION

Giant Cell Tumours (GCT) are benign tumours with aggressive potential that disrupt the local bony architecture, which can be especially problematic in peri-articular locations. Our aim was to assess the outcomes of patients with GCT of the distal ulna who were treated by resection without reconstruction.

METHODS

The study included 21 patients with distal ulna GCT that were treated with resection without reconstruction. There were 12 males and 9 females, with a mean age of 30.4years (range 14-45 years). The patients mean follow-up period was 4.4 years, with a two-year minimum follow-up.

RESULTS

Painful swelling was the presenting symtom in all cases. Nineteen patients had Campanacci grade 3 and two had Campanacci grade 2. The mean resected length of the distal ulna was 6.8 cm (range 4-10) cm. The Musculoskeletal Tumor Society score (MSTS) was 26.1. (range 22-28). Grip strength of the affected hand was reduced by 10.5% on average. (range 0%-16%). Two patients were having multi-centric disease on presentation and none of the cases had pathological fracture on presentation. One case had a local recurrence which was treated with surgery.

CONCLUSION

Based on current study, GCT of the distal ulna, en bloc resection without reconstruction can be recommended as a valuable treatment option for Campanacci grades 2 and 3 tumours. Resection of the distal end of the ulna without reconstruction results in excellent functional outcomes, with forearm rotational movement and hand function preserved. According to review of literature this is the largest series of GCT Ulna and we recommend a multicentre and comparitive studies on this topic.

摘要

引言

骨巨细胞瘤(GCT)是具有侵袭性潜能的良性肿瘤,会破坏局部骨质结构,在关节周围部位尤其棘手。我们的目的是评估接受尺骨远端骨巨细胞瘤切除术且未进行重建的患者的治疗效果。

方法

本研究纳入了21例接受尺骨远端骨巨细胞瘤切除术且未进行重建的患者。其中男性12例,女性9例,平均年龄30.4岁(范围14 - 45岁)。患者的平均随访时间为4.4年,最短随访时间为两年。

结果

所有病例的首发症状均为疼痛性肿胀。19例患者为Campanacci 3级,2例为Campanacci 2级。尺骨远端的平均切除长度为6.8厘米(范围4 - 10厘米)。肌肉骨骼肿瘤学会评分(MSTS)为26.1(范围22 - 28)。患侧手的握力平均降低了10.5%(范围0% - 16%)。2例患者初诊时患有多中心疾病,所有病例初诊时均无病理性骨折。1例出现局部复发,接受了手术治疗。

结论

基于当前研究,对于Campanacci 2级和3级肿瘤,尺骨远端骨巨细胞瘤整块切除且不进行重建可作为一种有价值的治疗选择。尺骨远端切除且不进行重建可带来出色的功能结果,保留了前臂旋转运动和手部功能。根据文献回顾,这是关于尺骨骨巨细胞瘤的最大系列研究,我们建议针对该主题开展多中心对比研究。

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