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中耳神经内分泌肿瘤中罕见的肺结节发现:一例病例报告及文献复习

A rare finding of pulmonary nodules in a middle ear neuroendocrine tumor: a case report and review of the literature.

作者信息

Alharbi Nader, Alotaibi Ghadah, Alabood Saleh, AlSulaiman Ibrahim, Bakry Essa

机构信息

Emergency Medicine Department, Buraidah Central Hospital, Al Imarah St, Assadah Dist, Buraidah 52361, Qassim, Saudi Arabia.

Clinical Sciences Department, College of Medicine, Princess Nourah Bint Abdulrahman University, Airport Rd, Al Narjis Dist, Riyadh 12211, Saudi Arabia.

出版信息

J Surg Case Rep. 2024 Oct 21;2024(10):rjae662. doi: 10.1093/jscr/rjae662. eCollection 2024 Oct.

Abstract

Neuroendocrine tumors (NETs) are usually found in the gastrointestinal tract and pancreas; however, they are rare in the middle ear. The presentation of vague symptoms, such as tinnitus and conductive hearing loss, complicates the diagnosis. We present a 46-year-old male with a history of right ear discharge and a previous canal wall-down mastoidectomy, suspected to have cholesteatoma recurrence. Imaging and surgery demonstrated a well-differentiated G1 NET in the middle ear. Postoperative metastatic workup revealed few pulmonary nodules needing ongoing observation. Middle-ear NETs are difficult to diagnose due to their rarity. This case underscores the importance of histological and immunohistochemical evaluation and the need for systemic assessment to rule out metastasis due to pulmonary nodules. We contribute to the limited literature highlighting the need to include NETs in the differential of middle ear masses and the usefulness of interdisciplinary teamwork.

摘要

神经内分泌肿瘤(NETs)通常见于胃肠道和胰腺;然而,它们在中耳中罕见。耳鸣和传导性听力损失等模糊症状的表现使诊断变得复杂。我们报告一名46岁男性,有右耳流脓病史且曾行开放式乳突根治术,怀疑胆脂瘤复发。影像学检查和手术显示中耳有一个高分化G1级NET。术后转移灶检查发现少数肺结节,需要持续观察。中耳NETs因其罕见而难以诊断。该病例强调了组织学和免疫组化评估的重要性以及进行全身评估以排除肺结节转移的必要性。我们为有限的文献做出了贡献,强调在中耳肿物鉴别诊断中需考虑NETs以及跨学科团队合作的有用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd04/11491658/abc657079fc0/rjae662f1.jpg

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