Regression of genetically determined polycystic kidney disease in murine organ culture.
作者信息
Avner E D, Sweeney W E, Piesco N P, Ellis D
出版信息
Experientia. 1986 Jan 15;42(1):77-80. doi: 10.1007/BF01975904.
PMID:3943602
Abstract
Cystic kidneys from the mutant CPK strain of C57BL/6J mice were cultured in serum-free organ culture. During 120 h of incubation in chemically-defined medium, CPK cystic tubular changes underwent complete regression. Environmental factors regulate the expression of genetically determined polycystic kidney disease in this model.
摘要
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