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A new model of glucocorticoid-induced metanephric maldevelopment.

作者信息

Avner E D, Sweeney W E, Piesco N P, Ellis D

出版信息

Experientia. 1984 May 15;40(5):489-90. doi: 10.1007/BF01952400.

Abstract

A new experimental model of glucocorticoid-induced tubular cyst formation has been developed in metanephric organ culture. The addition of cortisol (1.4 X 10(-5) M) to chemically defined serum-free culture medium produces cystic changes during in vitro nephrogenesis . The model isolates the role of glucocorticoids in experimental cyst formation.

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