RNA在生命早期进化中的开创性作用。
Pioneering role of RNA in the early evolution of life.
作者信息
Muñoz-Velasco Israel, Cruz-González Adrián, Hernández-Morales Ricardo, Campillo-Balderas José Alberto, Cottom-Salas Wolfgang, Jácome Rodrigo, Vázquez-Salazar Alberto
机构信息
Universidad Nacional Autónoma de México, Facultad de Ciencias, Departamento de Biología Celular, Mexico City, Mexico.
Universidad Nacional Autónoma de México, Facultad de Ciencias, Departamento de Biología Evolutiva, Mexico City, Mexico.
出版信息
Genet Mol Biol. 2024 Sep 2;47Suppl 1(Suppl 1):e20240028. doi: 10.1590/1678-4685-GMB-2024-0028. eCollection 2024.
The catalytic, regulatory and structural properties of RNA, combined with their extraordinary ubiquity in cellular processes, are consistent with the proposal that this molecule played a much more conspicuous role in heredity and metabolism during the early stages of biological evolution. This review explores the pivotal role of RNA in the earliest life forms and its relevance in modern biological systems. It examines current models that study the early evolution of life, providing insights into the primordial RNA world and its legacy in contemporary biology.
RNA的催化、调节和结构特性，以及它们在细胞过程中极其普遍的存在，与这样一种观点相一致，即这种分子在生物进化早期的遗传和代谢中发挥了更为显著的作用。这篇综述探讨了RNA在最早的生命形式中的关键作用及其在现代生物系统中的相关性。它研究了当前关于生命早期进化的模型，为原始RNA世界及其在当代生物学中的遗留影响提供了见解。
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