Lacroix Emilie, Fatur Karsten, Hay Phillipa, Touyz Stephen, Keshen Aaron
Department of Psychology, University of New Brunswick, 38 Dineen Drive, Fredericton, NB, Canada.
Translational Health Research Institute, School of Medicine, Western Sydney University, Campbelltown, Australia.
J Eat Disord. 2024 Oct 22;12(1):165. doi: 10.1186/s40337-024-01125-6.
Recent trials have shown promising results for the use of psychedelic-assisted therapies in treating severe refractory psychiatric illnesses, and there has been growing interest in examining the effectiveness of these therapies in treating eating disorders. To move forward in a safe, ethically sound, and scientifically rigorous manner, the field must address critical considerations. In this Comment article, we outline important risks and ethical considerations, along with methodological aspects that require careful consideration in the design of psychedelic-assisted therapy trials. We conclude by providing provisional guidelines for clinical research trials to help shape the future of this work, with the aim of investigating and employing the use of psychedelics for treating eating disorders in a manner that protects clients and research participants while maximizing methodological rigour.
近期的试验表明,使用迷幻剂辅助疗法治疗严重难治性精神疾病取得了令人鼓舞的成果,并且人们对研究这些疗法治疗饮食失调症的有效性越来越感兴趣。为了以安全、符合伦理且科学严谨的方式推进,该领域必须解决一些关键问题。在这篇评论文章中,我们概述了重要的风险和伦理考量,以及在迷幻剂辅助治疗试验设计中需要仔细考虑的方法学方面。我们通过为临床研究试验提供临时指南来结束本文,以帮助塑造这项工作的未来,目的是以保护客户和研究参与者的方式研究和应用迷幻剂治疗饮食失调症,同时最大限度地提高方法学的严谨性。