Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Department of Internal Medicine II and Gastroenterology, Emergency University Hospital of Bucharest, Romania.
J Med Life. 2024 Jul;17(7):660-664. doi: 10.25122/jml-2024-0304.
Sarcopenia, first introduced as a concept by I. Rosenberg in 1989, has since been extensively studied, particularly in its correlation with chronic diseases. In recent years, sarcopenia has been increasingly associated with advanced chronic liver disease, leading to a lower quality of life and poor outcomes for these patients. Studies have shown that sarcopenia has a prevalence of 33% in individuals with advanced chronic liver disease, impacting not only the patient's health but also contributing to increased healthcare costs. The prevalence of frailty in patients with advanced chronic liver disease is 27%. Given the high prevalence of sarcopenia and frailty in this population, early diagnosis and treatment are crucial to improving patient quality of life outcomes and reducing the strain on healthcare systems globally.
肌肉减少症最早由 I. Rosenberg 于 1989 年提出，此后得到了广泛研究，尤其是在与慢性疾病的相关性方面。近年来，肌肉减少症与晚期慢性肝病的关系越来越密切，导致这些患者的生活质量下降和预后不良。研究表明，晚期慢性肝病患者中肌肉减少症的患病率为 33%，不仅影响患者的健康，还导致医疗保健费用增加。晚期慢性肝病患者衰弱的患病率为 27%。鉴于该人群中肌肉减少症和衰弱的高患病率，早期诊断和治疗对于改善患者生活质量结局和减轻全球医疗系统负担至关重要。
