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豚鼠舌细胞的长期培养:一种合适的干扰素系统。

Long-term culture of guinea pig tongue cells: a suitable interferon system.

作者信息

Lackovic V, Kontsek P, Svobodová J, Borecký L

出版信息

Acta Virol. 1979 Mar;23(2):162-4.

PMID:39441
Abstract

The interferon system was investigated in a long-term culture of guinea pig tongue (GPT) cells. Interferon synthesis was induced with Newcastle disease virus (B strain) and f2 phage double-stranded RNA. Guinea pig interferons were about 2 times more active in cell cultures established from guinea pig embryos than in the GPT cells. Human leukocyte and mouse peritoneal cell interferons were active in this cell system also.

摘要

在豚鼠舌(GPT)细胞的长期培养中对干扰素系统进行了研究。用新城疫病毒(B株)和f2噬菌体双链RNA诱导干扰素合成。豚鼠干扰素在豚鼠胚胎建立的细胞培养物中的活性比在GPT细胞中高约2倍。人白细胞干扰素和小鼠腹腔细胞干扰素在该细胞系统中也有活性。

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