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机器人辅助根治性膀胱切除术后的皮输尿管造口术:经腹腔与经腹膜后技术的多中心对比研究。

Cutaneous ureterostomy following robot-assisted radical cystectomy: a multicenter comparative study of transperitoneal versus retroperitoneal techniques.

机构信息

Department of Urology, Tokushima University Graduate School of Biomedical Sciences, 3-18- 15 Kuramoto-cho, Tokushima, 770-8503, Japan.

Department of Urology, Tokushima Prefectural Central Hospital, 1-10-3 Kuramoto-cho, Tokushima, 770-8539, Japan.

出版信息

World J Urol. 2024 Oct 23;42(1):591. doi: 10.1007/s00345-024-05300-x.

DOI:10.1007/s00345-024-05300-x
PMID:39441314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11499339/
Abstract

BACKGROUND

The aim of this study was to evaluate the differences in perioperative outcomes between transperitoneal and retroperitoneal techniques in cutaneous ureterostomy (CUS).

METHODS

Between 2018 and 2023, 55 patients underwent CUS following robot-assisted radical cystectomy. Among the 55 patients, we compared 33 patients who underwent transperitoneal CUS (t-CUS) and 22 who underwent retroperitoneal CUS (r-CUS).

RESULTS

Compared with the r-CUS group, the t-CUS group had significantly shorter operative times (p < 0.001); significantly less estimated blood loss (p < 0.001); and significantly lower incidence of complications (Clavien-Dindo classification grade ≤ 2) within 30 days (p = 0.005). Unexpectedly, the incidence of ileus within 30 days was lower, though the difference was not statistically significant (p = 0.064). During the median follow-up period of 24.3 months, no ileus was observed in either group after 30 days postoperatively. There was no significant difference in the stent-free rate between the groups (p = 0.449). There were also no significant differences in the rates of change in estimated glomerular filtration rate from preoperatively at 3, 6, 12, and 24 months postoperatively between the groups (p = 0.590, p = 0.627, p = 0.741, and p = 0.778, respectively).

CONCLUSIONS

Compared with r-CUS, t-CUS was associated with a shorter operative time and lower incidence of perioperative complications, including gastrointestinal complications. We believe that t-CUS can be performed safely and effectively.

摘要

背景

本研究旨在评估经皮回肠造口术(cutaneous ureterostomy,CUS)中经腹腔与经腹膜两种技术的围手术期结局差异。

方法

2018 年至 2023 年,55 例机器人辅助根治性膀胱切除术患者接受 CUS。55 例患者中,我们比较了 33 例行经腹腔 CUS(transperitoneal CUS,t-CUS)和 22 例行经腹膜 CUS(retroperitoneal CUS,r-CUS)的患者。

结果

与 r-CUS 组相比,t-CUS 组的手术时间显著缩短(p<0.001);术中估计失血量显著减少(p<0.001);术后 30 天内并发症发生率(Clavien-Dindo 分级≤2 级)显著降低(p=0.005)。令人意外的是,术后 30 天内肠梗阻的发生率较低,但差异无统计学意义(p=0.064)。在中位随访 24.3 个月期间,两组患者术后 30 天后均未再发生肠梗阻。两组无支架率无显著差异(p=0.449)。两组术后 3、6、12 和 24 个月的估算肾小球滤过率(estimated glomerular filtration rate,eGFR)变化率也无显著差异(p=0.590、p=0.627、p=0.741 和 p=0.778)。

结论

与 r-CUS 相比,t-CUS 具有手术时间更短和围手术期并发症(包括胃肠道并发症)发生率更低的优势。我们认为 t-CUS 可以安全有效地实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/1f23f8ed42f9/345_2024_5300_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/4ded2bf33000/345_2024_5300_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/54a1a662f1ef/345_2024_5300_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/1f23f8ed42f9/345_2024_5300_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/4ded2bf33000/345_2024_5300_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/54a1a662f1ef/345_2024_5300_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d8/11499339/1f23f8ed42f9/345_2024_5300_Fig3_HTML.jpg

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本文引用的文献

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Int J Urol. 2024 Dec;31(12):1408-1413. doi: 10.1111/iju.15580. Epub 2024 Sep 10.
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Defining the association between the prolonged operative time and 90-day complications in patients undergoing radical cystectomy.确定根治性膀胱切除术患者手术时间延长与90天并发症之间的关联。
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Complete retroperitoneal cutaneous ureterostomy with robot-assisted radical cystectomy.
机器人辅助根治性膀胱切除术后完全腹膜后皮肤输尿管造口术
IJU Case Rep. 2024 Mar 5;7(3):250-254. doi: 10.1002/iju5.12717. eCollection 2024 May.
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Robotic-assisted radical cystectomy with cutaneous ureterostomies: a contemporary multicenter analysis.机器人辅助根治性膀胱切除术加皮造口术:当代多中心分析。
World J Urol. 2024 Apr 23;42(1):251. doi: 10.1007/s00345-024-04942-1.
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Surgical outcomes and predictive value for major complications of robot-assisted radical cystectomy of real-world data in a single institution in Japan.日本一家机构的真实世界数据中机器人辅助根治性膀胱切除术的手术结果及主要并发症的预测价值
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Cutaneous Ureterostomy Following Radical Cystectomy for Bladder Cancer: A Contemporary Series.膀胱癌根治性膀胱切除术后的皮输尿管造口术:当代系列研究。
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