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东南亚国家儿童营养不良三重负担的患病率及关键决定因素:在适应性社会生态框架内的系统评价和荟萃分析

Prevalence and key determinants of the triple burden of childhood malnutrition in Southeast Asian countries: a systematic review and meta-analysis within an adapted socio-ecological framework.

作者信息

Tan Pui Yee, Chan Chong Ling, Som Somphos Vicheth, Dye Louise, Moore J Bernadette, Caton Samantha, Gong YunYun

机构信息

School of Food Science and Nutrition, Faculty of Environment, University of Leeds, Leeds, UK.

Section of Infectious Diseases, Department of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

出版信息

Crit Rev Food Sci Nutr. 2024 Oct 23:1-15. doi: 10.1080/10408398.2024.2419539.

Abstract

The triple burden of malnutrition (TBM) is increasing globally, but significant evidence gaps exist regarding its burden and drivers among children in Southeast Asian (SEA) countries. We systematically searched four databases (PROSPERO-CRD42023420129) and Google Scholar through February 2024. We assessed stunting and overweight prevalence among children aged 0-18 years old across four SEA countries (Indonesia, Malaysia, Thailand, and Vietnam) from recent national surveys. We conducted random-effect meta-analyses to estimate the pooled prevalence of micronutrient deficiencies, and the pooled odds ratio for TBM-associated determinants using an adapted socio-ecological framework. 176 studies were included for systematic review, with 132 studies eligible for meta-analysis. Our findings illustrate significant variation in TBM across countries, dependent on region, age, and sex. Pooled prevalence [95% CI] of anemia, iron, vitamin A, and D deficiencies were 25% [22, 29], 14% [10, 18], 6% [4, 8], and 40% [32, 48], respectively (I>90%). Determinants of the TBM included child-individual factors, poor early-life nutrition, and family household characteristics including maternal nutrition and education, socioeconomic, family size, sanitation, and food security. However, macro-level environmental impacts were less documented. Our findings emphasize the need for robust, timely monitoring of TBM data, including micronutrient biomarkers, and targeted policy intervention in SEA countries.

摘要

全球营养不良的三重负担(TBM)正在增加,但在东南亚(SEA)国家儿童中,关于其负担和驱动因素存在重大证据空白。我们通过2024年2月系统性检索了四个数据库(PROSPERO-CRD42023420129)和谷歌学术。我们根据近期的全国调查评估了四个东南亚国家(印度尼西亚、马来西亚、泰国和越南)0至18岁儿童的发育迟缓与超重患病率。我们进行了随机效应荟萃分析,以估计微量营养素缺乏的合并患病率,以及使用适应性社会生态框架的TBM相关决定因素的合并优势比。纳入176项研究进行系统评价,其中132项研究符合荟萃分析条件。我们的研究结果表明,TBM在不同国家存在显著差异,取决于地区、年龄和性别。贫血、铁、维生素A和D缺乏的合并患病率[95%CI]分别为25%[22,29]、14%[10,18]、6%[4,8]和40%[32,48](I>90%)。TBM的决定因素包括儿童个体因素、早期营养不良以及家庭特征,包括母亲营养和教育、社会经济状况、家庭规模、卫生设施和粮食安全。然而,宏观层面的环境影响记录较少。我们的研究结果强调,在东南亚国家需要对TBM数据(包括微量营养素生物标志物)进行有力、及时的监测,并进行有针对性的政策干预。

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