• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

"A Time to Tear Down and a Time to Mend": The Role of Eicosanoids in Atherosclerosis.

作者信息

Sherratt Samuel C R, Mason R Preston, Libby Peter, Bhatt Deepak L

机构信息

Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY (S.C.R.S., D.L.B.).

Elucida Research, Beverly, MA (S.C.R.S., R.P.M.).

出版信息

Arterioscler Thromb Vasc Biol. 2024 Nov;44(11):2258-2263. doi: 10.1161/ATVBAHA.124.319570. Epub 2024 Oct 23.

DOI:10.1161/ATVBAHA.124.319570
PMID:39441911
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11495529/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31b/11495529/060235e44ce0/atv-44-2258-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31b/11495529/a3b63fce9816/atv-44-2258-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31b/11495529/060235e44ce0/atv-44-2258-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31b/11495529/a3b63fce9816/atv-44-2258-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b31b/11495529/060235e44ce0/atv-44-2258-g003.jpg

相似文献

1
"A Time to Tear Down and a Time to Mend": The Role of Eicosanoids in Atherosclerosis.“拆毁有时,建造有时”:类花生酸在动脉粥样硬化中的作用
Arterioscler Thromb Vasc Biol. 2024 Nov;44(11):2258-2263. doi: 10.1161/ATVBAHA.124.319570. Epub 2024 Oct 23.
2
A 'desaturase hypothesis' for atherosclerosis: Janus-faced enzymes in omega-6 and omega-3 polyunsaturated fatty acid metabolism.动脉粥样硬化的“去饱和酶假说”:ω-6和ω-3多不饱和脂肪酸代谢中的双面酶
J Nutrigenet Nutrigenomics. 2009;2(3):129-39. doi: 10.1159/000238177. Epub 2009 Sep 23.
3
Essential polyunsaturated fatty acids, inflammation, atherosclerosis and cardiovascular diseases.必需多不饱和脂肪酸、炎症、动脉粥样硬化与心血管疾病
Subcell Biochem. 2007;42:283-97. doi: 10.1007/1-4020-5688-5_13.
4
The effect of enterolactone on liver lipid precursors of inflammation.肠内酯对炎症肝脂质前体的影响。
Life Sci. 2019 Mar 15;221:341-347. doi: 10.1016/j.lfs.2019.02.044. Epub 2019 Feb 22.
5
Effect of individual fatty acids of omega-6 and omega-3 type on human immune status and role of eicosanoids.ω-6和ω-3型单脂肪酸对人体免疫状态的影响以及类花生酸的作用。
Nutrition. 2000 Feb;16(2):143-5. doi: 10.1016/s0899-9007(99)00256-7.
6
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.ω-3长链多不饱和脂肪酸在视网膜健康与疾病中的作用。
Prog Retin Eye Res. 2005 Jan;24(1):87-138. doi: 10.1016/j.preteyeres.2004.06.002.
7
The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability.海洋 ω-3(n-3)脂肪酸在炎症过程、动脉粥样硬化和斑块稳定性中的作用。
Mol Nutr Food Res. 2012 Jul;56(7):1073-80. doi: 10.1002/mnfr.201100710.
8
Systematic metabolomic analysis of eicosanoids after omega-3 polyunsaturated fatty acid supplementation by a highly specific liquid chromatography-tandem mass spectrometry-based method.采用基于高特异性液相色谱-串联质谱法对ω-3多不饱和脂肪酸补充后类二十烷酸进行系统代谢组学分析。
J Proteome Res. 2015 Apr 3;14(4):1843-53. doi: 10.1021/pr501200u. Epub 2015 Mar 17.
9
Eicosanoids: Atherosclerosis and cardiometabolic health.类二十烷酸:动脉粥样硬化与心脏代谢健康。
J Clin Transl Endocrinol. 2020 Feb 3;19:100216. doi: 10.1016/j.jcte.2020.100216. eCollection 2020 Mar.
10
[The individual fatty acids in blood plasma, erythrocytes and lipoproteins. The comparison of tests results of patients with ischemic heart disease and volunteers].[血浆、红细胞和脂蛋白中的个体脂肪酸。缺血性心脏病患者与志愿者的检测结果比较]
Klin Lab Diagn. 2012 Jul(7):3-8.

引用本文的文献

1
12/15-lipoxygenase mediates disturbed flow-induced endothelial dysfunction and atherosclerosis.12/15-脂氧合酶介导血流紊乱诱导的内皮功能障碍和动脉粥样硬化。
Mol Med. 2025 Jul 15;31(1):257. doi: 10.1186/s10020-025-01297-0.
2
Endothelial soluble epoxide hydrolase links polyunsaturated fatty acid metabolism to oxidative stress and atherosclerosis progression.内皮可溶性环氧化物水解酶将多不饱和脂肪酸代谢与氧化应激和动脉粥样硬化进展联系起来。
Redox Biol. 2025 Jun 14;85:103730. doi: 10.1016/j.redox.2025.103730.
3
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.

本文引用的文献

1
Eicosapentaenoic Acid Improves Endothelial Nitric Oxide Bioavailability Via Changes in Protein Expression During Inflammation.二十碳五烯酸通过炎症过程中的蛋白表达变化改善内皮型一氧化氮生物利用度。
J Am Heart Assoc. 2024 Jul 16;13(14):e034076. doi: 10.1161/JAHA.123.034076. Epub 2024 Jul 3.
2
Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA).随机试验评估联合治疗-他汀类药物和二十碳五烯酸(RESPECT-EPA)在二级预防中的疗效。
Circulation. 2024 Aug 6;150(6):425-434. doi: 10.1161/CIRCULATIONAHA.123.065520. Epub 2024 Jun 14.
3
Do patients benefit from omega-3 fatty acids?
依洛尤单抗乙酯对基线低密度脂蛋白胆固醇的心血管结局影响:REDUCE-IT随机试验的二次分析
J Am Heart Assoc. 2025 Mar 4;14(5):e038656. doi: 10.1161/JAHA.124.038656. Epub 2025 Feb 19.
患者是否能从 ω-3 脂肪酸中获益?
Cardiovasc Res. 2024 Feb 17;119(18):2884-2901. doi: 10.1093/cvr/cvad188.
4
Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.回复:未能将标准检测限或定量限标准应用于特殊促消退介质分析,会错误地描述它们在生物样品中的存在情况。
Nat Commun. 2023 Nov 10;14(1):7293. doi: 10.1038/s41467-023-41767-9.
5
Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.未能将标准检测限或定量限标准应用于特殊促消退介质分析会错误地判定它们在生物样品中的存在情况。
Nat Commun. 2023 Nov 9;14(1):7172. doi: 10.1038/s41467-023-41766-w.
6
Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?特殊促消退脂质介质的形成、信号传导与产生——目前有哪些证据?
Front Pharmacol. 2022 Mar 2;13:838782. doi: 10.3389/fphar.2022.838782. eCollection 2022.
7
The changing landscape of atherosclerosis.动脉粥样硬化的变化格局。
Nature. 2021 Apr;592(7855):524-533. doi: 10.1038/s41586-021-03392-8. Epub 2021 Apr 21.
8
Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chronic inflammation.在患有重度抑郁症和慢性炎症的患者中,补充二十碳五烯酸后,循环中抗炎和促解决的脂质介质呈剂量和时间依赖性增加。
Prostaglandins Leukot Essent Fatty Acids. 2021 Jan;164:102219. doi: 10.1016/j.plefa.2020.102219. Epub 2020 Dec 5.
9
Effects of Epeleuton, a Novel Synthetic Second-Generation n-3 Fatty Acid, on Non-Alcoholic Fatty Liver Disease, Triglycerides, Glycemic Control, and Cardiometabolic and Inflammatory Markers.新型合成第二代 n-3 脂肪酸 Epeleuton 对非酒精性脂肪肝、甘油三酯、血糖控制以及心血管代谢和炎症标志物的影响。
J Am Heart Assoc. 2020 Aug 18;9(16):e016334. doi: 10.1161/JAHA.119.016334. Epub 2020 Aug 11.
10
Eicosapentaenoic acid (EPA) has optimal chain length and degree of unsaturation to inhibit oxidation of small dense LDL and membrane cholesterol domains as compared to related fatty acids in vitro.二十碳五烯酸(EPA)具有最佳的链长和不饱和度,可抑制小而密 LDL 和膜胆固醇结构域的氧化,这与体外的相关脂肪酸相比。
Biochim Biophys Acta Biomembr. 2020 Jul 1;1862(7):183254. doi: 10.1016/j.bbamem.2020.183254. Epub 2020 Mar 2.