Facultad de Medicina Humana, Universidad Nacional de San Antonio Abad del Cusco, Cusco, Perú.
ASOCIEMH-CUSCO, Facultad de Medicina Humana, Universidad Nacional de San Antonio Abad del Cusco, Cusco, Perú.
Rev Peru Med Exp Salud Publica. 2024 Oct 21;41(3):287-293. doi: 10.17843/rpmesp.2024.413.13378.
Motivation for the study. There are few clinical and survival studies in Peru on thyroid cancer.
Main findings. Between the years 2010 to 2020, differentiated thyroid cancer was more frequent in women with early-stage disease, but survival was lower at five years compared to reports from other countries.
Implications. Thyroid cancer has increased in recent decades worldwide. It is important to have specialized and decentralized centers for the initial management and follow-up of these patients to avoid long-term complications or fatal outcomes and to have updated epidemiological information.
This study aimed at studying the clinical and anatomopathological characteristics, treatment and survival of patients with differentiated thyroid cancer. A retrospective cohort study was conducted with data from 150 patients from a Peruvian hospital between the years 2010 to 2020. Characteristics and survival (Kaplan-Meier method) were described. The mean age was 48.3 years, 130 participants (86.7%) were women and the most frequent histologic type was papillary 94.6%. Of the participants, 74.2% had TNM stage I, 70.7% had total thyroidectomy and 68.7% received radioactive iodine. Overall survival at 5 years was 89.3%, being lower in those with TNM stage IV and higher in those who used radioactive iodine. In conclusion, in a hospital in Cusco, differentiated thyroid cancer was more frequent in women and survival was lower compared to reports from other countries.
研究动机。秘鲁鲜有关于甲状腺癌的临床和生存研究。
主要发现。2010 年至 2020 年间，患有早期疾病的女性中分化型甲状腺癌更为常见，但五年生存率低于其他国家的报告。
意义。近几十年来，全球范围内甲状腺癌的发病率有所增加。拥有专门的、分散的中心来对这些患者进行初始管理和随访，以避免长期并发症或致命结局，并获取最新的流行病学信息非常重要。
本研究旨在研究秘鲁一家医院的 150 例分化型甲状腺癌患者的临床和解剖病理学特征、治疗方法和生存情况。这是一项回顾性队列研究，数据来自 2010 年至 2020 年期间的 150 名患者。描述了特征和生存情况（Kaplan-Meier 法）。平均年龄为 48.3 岁，130 名参与者（86.7%）为女性，最常见的组织学类型为乳头状 94.6%。参与者中 74.2%为 TNM 分期 I 期，70.7%接受了全甲状腺切除术，68.7%接受了放射性碘治疗。5 年总生存率为 89.3%，TNM 分期 IV 期患者生存率较低，使用放射性碘治疗的患者生存率较高。总之，在库斯科的一家医院，女性中分化型甲状腺癌更为常见，且生存率低于其他国家的报告。
