Slovis C M, Talley J D, Pitts R B
J Chronic Dis. 1986;39(2):121-6. doi: 10.1016/0021-9681(86)90068-8.
Conflicting results have arisen from studies concerning the correlation (if any) between climatological changes and the frequency of painful episodes in the sickle cell population. During a 13 month period records of 71 patients with hemoglobin genotypes SS or SC were reviewed. Data analysis failed to reveal an association between the frequency of painful sickle cell crisis and a number of weather and environmental variables. We were unable to demonstrate relationships between the climatologic factors of temperature, humidity, carbon monoxide level and precipitation in the frequency of 362 pain crises in 71 sickle cell patients during a 13 month period.
关于气候学变化与镰状细胞病患者疼痛发作频率之间的相关性（如果存在的话），各项研究得出了相互矛盾的结果。在13个月的时间里，对71例血红蛋白基因型为SS或SC的患者记录进行了回顾。数据分析未能揭示镰状细胞疼痛危机的频率与一些天气和环境变量之间的关联。在13个月的时间里，我们未能证明71例镰状细胞病患者的362次疼痛危机发作频率与温度、湿度、一氧化碳水平和降水量等气候因素之间存在关联。
