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Clues into Wnt cell surface signalosomes and its biogenesis.
Trends Biochem Sci. 2024 Dec;49(12):1042-1045. doi: 10.1016/j.tibs.2024.09.007. Epub 2024 Oct 22.
3
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
Nature. 2017 May 11;545(7653):234-237. doi: 10.1038/nature22306. Epub 2017 May 3.
4
Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2218238120. doi: 10.1073/pnas.2218238120. Epub 2023 Mar 9.
5
Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling.
Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a007880. doi: 10.1101/cshperspect.a007880.
6
The structural basis of DKK-mediated inhibition of Wnt/LRP signaling.
Sci Signal. 2012 May 15;5(224):pe22. doi: 10.1126/scisignal.2003028.
7
Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens.
Dev Cell. 2024 Jan 22;59(2):244-261.e6. doi: 10.1016/j.devcel.2023.11.027. Epub 2023 Dec 27.
8
Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes.
J Cell Biol. 2013 Feb 18;200(4):419-28. doi: 10.1083/jcb.201206096. Epub 2013 Feb 11.
9
Frizzled receptors (FZDs) in Wnt signaling: potential therapeutic targets for human cancers.
Acta Pharmacol Sin. 2024 Aug;45(8):1556-1570. doi: 10.1038/s41401-024-01270-3. Epub 2024 Apr 17.
10
Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling and .
J Biol Chem. 2020 Jan 24;295(4):1021-1035. doi: 10.1074/jbc.RA119.010285. Epub 2019 Dec 13.

本文引用的文献

1
Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain.
Science. 2024 May 3;384(6695):573-579. doi: 10.1126/science.ade6970. Epub 2024 May 2.
3
Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling.
Cell. 2023 Nov 9;186(23):5028-5040.e14. doi: 10.1016/j.cell.2023.09.021. Epub 2023 Oct 17.
4
The logistics of Wnt production and delivery.
Curr Top Dev Biol. 2023;153:1-60. doi: 10.1016/bs.ctdb.2023.01.006. Epub 2023 Feb 25.
5
Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2218238120. doi: 10.1073/pnas.2218238120. Epub 2023 Mar 9.
6
Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature. 2022 Jul;607(7920):816-822. doi: 10.1038/s41586-022-04952-2. Epub 2022 Jul 13.
7
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators.
Annu Rev Biochem. 2022 Jun 21;91:571-598. doi: 10.1146/annurev-biochem-040320-103615. Epub 2022 Mar 18.
8
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.
Cell Stem Cell. 2020 Nov 5;27(5):840-851.e6. doi: 10.1016/j.stem.2020.07.020. Epub 2020 Aug 19.
9
Calnexin cycle - structural features of the ER chaperone system.
FEBS J. 2020 Oct;287(20):4322-4340. doi: 10.1111/febs.15330. Epub 2020 Apr 27.
10
Wnt Signaling and Drug Resistance in Cancer.
Mol Pharmacol. 2020 Feb;97(2):72-89. doi: 10.1124/mol.119.117978. Epub 2019 Dec 1.

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