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阻塞性睡眠呼吸暂停患者时间感知的差异。

Differences in time perception in patients with obstructive sleep apnea.

作者信息

Özdemir İnan, Bek Semai, Aksu Serkan, Kutlu Gülnihal

机构信息

Clinic of Neurology, Bingol State Hospital, Merkez, 12000, Bingöl, Turkey.

Department of Neurology, Faculty of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey.

出版信息

Neurol Sci. 2025 Mar;46(3):1329-1337. doi: 10.1007/s10072-024-07827-8. Epub 2024 Oct 24.

DOI:10.1007/s10072-024-07827-8
PMID:39443436
Abstract

BACKGROUND

Obstructive sleep apnea (OSA) is a condition that occurs due to complete (apnea) and partial (hypopnea) obstruction in the upper airways during sleep. Hypoxia is one of the key factors contributing to the development of symptoms of obstructive sleep apnea and OSA-related diseases.

OBJECTIVE

The present study aimed to evaluate time perception differences between patients with OSA and healthy individuals, as well as among different OSA severity groups.

METHODS

Twenty severe OSA, twenty moderate OSA, twenty mild OSA patients, and twenty healthy volunteers without OSA were included in the study. Scales were administered to the participants. Time perception tests were administered to evaluate perceptual timing.

RESULTS

In the paced motor timing test, a difference was observed between the OSA ( +) group and the OSA (-) group. In the Time Estimation Test, a difference was observed between the OSA ( +) group and the OSA (-) group and their subgroups.

CONCLUSION

The internal clock works slower in the OSA ( +) group. When subgroups were compared based on the degree of OSA, the internal clock worked slower as we transitioned from the OSA (-) group to the severe OSA group. It is considered that as you move from the OSA (-) group to the severe OSA group, the switch between pacemaker and accumulator is disrupted due to the decrease in attention. Recurrent hypoxia observed in OSA may alter the perception of time by affecting attention.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)是一种在睡眠期间由于上呼吸道完全(呼吸暂停)和部分(呼吸不足)阻塞而发生的病症。缺氧是导致阻塞性睡眠呼吸暂停症状和OSA相关疾病发展的关键因素之一。

目的

本研究旨在评估OSA患者与健康个体之间以及不同OSA严重程度组之间的时间感知差异。

方法

本研究纳入了20名重度OSA患者、20名中度OSA患者、20名轻度OSA患者以及20名无OSA的健康志愿者。对参与者进行量表测试。进行时间感知测试以评估感知计时。

结果

在同步运动计时测试中,观察到OSA(+)组和OSA(-)组之间存在差异。在时间估计测试中,观察到OSA(+)组与其亚组之间存在差异。

结论

OSA(+)组的内部时钟运行较慢。当根据OSA程度比较亚组时,随着我们从OSA(-)组过渡到重度OSA组,内部时钟运行得更慢。据认为,当从OSA(-)组转变为重度OSA组时,由于注意力下降,起搏器和累加器之间的切换受到干扰。OSA中观察到的反复缺氧可能通过影响注意力来改变时间感知。

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