Department of Infectious Diseases, Clinical Immunology and Allergy, Division of Medicine, Lyell McEwin Hospital, Adelaide, South Australia, Australia.
Centre for Antibiotic Allergy and Research, Department of Infectious Diseases and Immunology, Austin Health, Melbourne, Victoria, Australia.
Intern Med J. 2024 Nov;54(11):1883-1893. doi: 10.1111/imj.16543. Epub 2024 Oct 23.
Penicillin allergy is a significant burden on patient, prescribing and hospital outcomes. There has been increasing interest in the incorporation of penicillin allergy testing (i.e. delabelling) into antimicrobial stewardship (AMS) programmes to reduce the burden of penicillin allergy labels and improve prescribing. In particular, there has been a focus on point-of-care penicillin allergy assessment and direct oral challenge for low-risk phenotypes. The National Antibiotic Allergy Network has provided a guide to assist AMS clinicians with the incorporation of penicillin allergy programmes, in particular direct oral challenge, into Australian hospitals.
青霉素过敏是患者、处方和医院结果的重大负担。人们越来越关注将青霉素过敏测试(即去标签)纳入抗菌药物管理(AMS)计划,以减轻青霉素过敏标签的负担并改善处方。特别是,人们一直关注在低风险表型中进行即时的青霉素过敏评估和直接口服挑战。国家抗生素过敏网络提供了一份指南,以帮助 AMS 临床医生将青霉素过敏方案,特别是直接口服挑战,纳入澳大利亚医院。