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隐形眼镜紫外线透过率与近视进展的关系:一项大规模回顾性队列研究。

The relationship between contact lens ultraviolet light transmittance and myopia progression: a large-scale retrospective cohort study.

作者信息

Okada Hiroyuki, Yoshida Masao, Takeuchi Masaki, Okada Eiichi, Mizuki Nobuhisa

机构信息

Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan.

Okada Eye Clinic, Yokohama, Kanagawa 234-0054, Japan.

出版信息

Precis Clin Med. 2024 Oct 11;7(4):pbae022. doi: 10.1093/pcmedi/pbae022. eCollection 2024 Dec.

Abstract

BACKGROUND

The prevalence of myopia is increasing dramatically around the world, and many studies have suggested the possibility that ultraviolet (UV) light is effective to prevent the onset and progression of myopia. However, UV is a risk factor for diseases that cause refractive errors such as cataract and pterygium. In this study, we evaluated the relationship between UV exposure and myopia progression.

METHODS

The dataset consisted of a total of 337 396 eyes of patients in the 12-to-29-year age range, who were prescribed soft contact lenses (SCL) for refractive error at Okada Eye Clinic in Japan between 2002 and 2011. They were tracked over a five-year period and did not change the type of SCL. In this retrospective cohort study based on medical records, we divided patients into two groups, one prescribed SCL with UV protection (UV-SCL), and another prescribed SCL without UV protection (UV + SCL).

RESULTS

Change in refractive power over five years was measured and results compared. It was -0.413 diopter (D) in the UV-SCL group and -0.462 D in the UV + SCL group. Thus, the progression of myopia was slower in the UV-SCL group. The results were also analyzed separately by gender and degree of myopia at the time of initial prescription, which all showed significant differences (< 0.001).

CONCLUSION

Results suggest that UV exposure may advance myopia. Further research is needed to investigate the underlying mechanisms that could explain this.

摘要

背景

全球近视患病率正在急剧上升,许多研究表明紫外线(UV)可能对预防近视的发生和发展有效。然而,紫外线是导致屈光不正的疾病(如白内障和翼状胬肉)的危险因素。在本研究中,我们评估了紫外线暴露与近视进展之间的关系。

方法

数据集包括2002年至2011年期间在日本冈田眼科诊所因屈光不正而佩戴软性隐形眼镜(SCL)的12至29岁患者的总共337396只眼睛。他们被追踪了五年,并且没有更换SCL的类型。在这项基于医疗记录的回顾性队列研究中,我们将患者分为两组,一组佩戴具有紫外线防护功能的SCL(UV-SCL),另一组佩戴没有紫外线防护功能的SCL(UV+SCL)。

结果

测量了五年内的屈光力变化并比较了结果。UV-SCL组为-0.413屈光度(D),UV+SCL组为-0.462D。因此,UV-SCL组的近视进展较慢。还按性别和初始处方时的近视程度分别进行了分析,所有结果均显示出显著差异(<0.001)。

结论

结果表明紫外线暴露可能会促进近视。需要进一步研究以探究能够解释这一现象的潜在机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca9/11497595/cbf9cb2086c6/pbae022fig1g.jpg

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