Knutson Kristen L, Reid Kathryn J, Karanth Sunaina, Kim Nathan, Abbott Sabra M, Alexandria Shaina J, Harrington Katharine, Thomas S Justin, Lewis Cora E, Schreiner Pamela J, Carnethon Mercedes R
Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Department of Preventive Medicine, Northwestern Feinberg School of Medicine, Chicago, IL, USA.
Sleep Adv. 2024 Sep 26;5(1):zpae071. doi: 10.1093/sleepadvances/zpae071. eCollection 2024.
Sleep and circadian disturbances are common and are experienced more often by Black compared to White individuals. We conducted an observational study of sleep that was ancillary to an ongoing cohort study, Coronary Artery Disease in Young Adults (CARDIA). The goal of the ancillary study will be to examine potential determinants of sleep/circadian disparities between Black and White adults in future analyses. Herein we describe the study design and methodology. Our ancillary study coincided with the Year 35 examination of the CARDIA study and was conducted in two phases (due to the SARS-COV-2 pandemic). Phase 1 involved only questionnaires to assess chronotype, restless legs syndrome, and the household sleep environment. Phase 2 involved three additional questionnaires to assess sleep quality, daytime sleepiness and insomnia symptoms, as well as two sleep devices. Participants wore a wrist activity monitor to assess sleep-wake patterns and light levels for 7 days and a home sleep apnea test for 1 night. A subset also had devices objectively record light, temperature, and sound levels in their bedrooms for 7 days. Sample sizes ranged based on assessment from 2200 to 2400, completing Phase 1 questionnaires, 899 with valid wrist actigraphy data, and 619 with a valid sleep apnea test. The data will be part of the full CARDIA dataset, which is available to researchers.
睡眠和昼夜节律紊乱很常见，而且与白人相比，黑人经历这些问题的频率更高。我们对睡眠进行了一项观察性研究，该研究是正在进行的队列研究“青年成人冠状动脉疾病（CARDIA）”的附属研究。附属研究的目标是在未来的分析中检查黑人和白人成年人睡眠/昼夜节律差异的潜在决定因素。在此我们描述研究设计和方法。我们的附属研究与CARDIA研究的第35年检查同时进行，并且分两个阶段进行（由于SARS-CoV-2大流行）。第一阶段仅涉及问卷，以评估昼夜类型、不宁腿综合征和家庭睡眠环境。第二阶段涉及另外三份问卷，以评估睡眠质量、白天嗜睡和失眠症状，以及两种睡眠设备。参与者佩戴腕部活动监测器7天以评估睡眠-觉醒模式和光照水平，并进行1晚的家庭睡眠呼吸暂停测试。一部分参与者还让设备客观记录其卧室7天的光照、温度和声音水平。样本量根据评估范围从2200至2400不等，完成第一阶段问卷，899人有有效的腕部活动记录仪数据，619人有有效的睡眠呼吸暂停测试数据。这些数据将成为完整CARDIA数据集的一部分，可供研究人员使用。
