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试点研究:干细胞疗法和切碎软骨在二次鼻整形病例中的应用 临床结果:金色土耳其软糖。

Pilot Study: Use of Stem Cell Therapy and Diced Cartilage in Secondary Rhinoplasty Cases Clinical Outcomes: The Golden Turkish Delight.

作者信息

Unlu Ramazan Erkin, Ozmut Ozer, Ergani Hasan Murat, Yasar Burak, Yildirim Furkan

机构信息

From the Plastic and Reconstructive Surgery, Ankara Bilkent City Hospital, Ankara, Turkey.

出版信息

Plast Reconstr Surg Glob Open. 2024 Oct 23;12(10):e6243. doi: 10.1097/GOX.0000000000006243. eCollection 2024 Oct.

DOI:10.1097/GOX.0000000000006243
PMID:39444535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11498922/
Abstract

BACKGROUND

Although many techniques in the secondary rhinoplasty field have been developed in recent years, there are debates regarding achieving results with a high satisfaction rate. We aimed to share the surgical use technique in secondary rhinoplasty patients by enriching the Turkish delight technique with mesenchymal stem cells, which we described as the golden Turkish delight (GTD) technique, and the long-term patient satisfaction results.

METHODS

The study was planned as prospective research, and 30 secondary rhinoplasty patients who presented to our service for rhinoplasty were included. The GTD technique was applied to these patients. The patient's satisfaction with the surgical procedure was evaluated at least 9-12 months after the surgery, and the Global Aesthetic Improvement Scale (GAIS) was used as a measurement tool.

RESULTS

Of the participants, the satisfaction levels of 30 patients were evaluated with a 1-year follow-up on average, and the rate of those who improved was found to be 80% using the GAIS score. The rate of those with high GAIS scores and those with high satisfaction levels was approximately 56%. Twenty percent of the patients were not satisfied with the result.

CONCLUSIONS

When we evaluate the postoperative 1-year results of our patients in terms of satisfaction and complications, we may state that the absorption that may occur in the Turkish delight technique over time could give better results with the GTD technique. In addition to GTD and fat graft support, regenerative medicine products such as stromal vascular fraction are very effective in obtaining favorable results.

摘要

背景

尽管近年来鼻整形修复领域已开发出多种技术,但在实现高满意率的效果方面仍存在争议。我们旨在通过用间充质干细胞丰富土耳其软糖技术(我们将其描述为金土耳其软糖(GTD)技术)来分享鼻整形修复患者的手术应用技术以及患者的长期满意度结果。

方法

该研究计划为前瞻性研究,纳入了30名到我们科室进行鼻整形修复的患者。对这些患者应用了GTD技术。在手术后至少9至12个月评估患者对手术的满意度,并使用全球美学改善量表(GAIS)作为测量工具。

结果

在参与者中,平均对30名患者进行了1年的随访评估其满意度,使用GAIS评分发现改善率为80%。GAIS评分高和满意度高的患者比例约为56%。20%的患者对结果不满意。

结论

当我们从满意度和并发症方面评估患者术后1年的结果时,可以说随着时间推移土耳其软糖技术可能出现的吸收现象,GTD技术可能会产生更好的结果。除了GTD和脂肪移植支持外,诸如基质血管成分等再生医学产品在获得良好结果方面非常有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/0bfb1de4b051/gox-12-e6243-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/7fa67aa58794/gox-12-e6243-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/53d2addbf5a8/gox-12-e6243-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/6d7eae8fd746/gox-12-e6243-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/0bfb1de4b051/gox-12-e6243-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/7fa67aa58794/gox-12-e6243-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/53d2addbf5a8/gox-12-e6243-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/6d7eae8fd746/gox-12-e6243-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a826/11498922/0bfb1de4b051/gox-12-e6243-g004.jpg

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Aesthet Surg J. 2023 Aug 17;43(9):964-971. doi: 10.1093/asj/sjad154.
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Diced Cartilage Techniques in Rhinoplasty.隆鼻术中的软骨切块技术。
Aesthetic Plast Surg. 2022 Jun;46(3):1369-1377. doi: 10.1007/s00266-021-02628-2. Epub 2021 Nov 3.
3
The Silicone Turkish Delight for Dorsal Augmentation in Rhinoplasty.
硅胶土耳其软糖在鼻整形术的背侧隆凸中的应用。
J Craniofac Surg. 2021 Oct 1;32(7):2524-2527. doi: 10.1097/SCS.0000000000007674.
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Improving Low-Density Fat by Condensing Cellular and Collagen Content through a Mechanical Process: Basic Research and Clinical Applications.通过机械过程浓缩细胞和胶原蛋白含量以改善低密度脂肪:基础研究和临床应用。
Plast Reconstr Surg. 2021 Nov 1;148(5):1029-1039. doi: 10.1097/PRS.0000000000008484.
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