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全三维内镜主动脉瓣置换术:单中心初步结果与经验

Totally 3D endoscopic aortic valve replacement: initial results and experience from a single center.

作者信息

Nguyen Huu Cong, Pham Dat Thanh

机构信息

E Hospital, Hanoi, Vietnam.

University of Medicine and Pharmacy - Vietnam National University, Hanoi, Vietnam.

出版信息

Front Cardiovasc Med. 2024 Oct 9;11:1468452. doi: 10.3389/fcvm.2024.1468452. eCollection 2024.

Abstract

OBJECTIVE

This study aimed to evaluate the feasibility and initial outcomes of totally endoscopic aortic valve replacement (TEAVR) performed via a single working port at the fourth intercostal space (ICS) utilizing a 3D endoscopic system.

METHODS

A retrospective observational study was conducted on 35 consecutive patients who underwent TEAVR over a six-month period from December 2023 to June 2024. Patient selection was based on the presence of isolated aortic valve disease without the need for ascending aorta replacement or aortic root enlargement. A 4 cm single working port was created at the 4th ICS, extending from the right mid-axillary to the anterior axillary line. A 10-mm trocar for a 3D endoscope was placed at the right anterior-axillary line. Peripheral cardiopulmonary bypass (CPB) was established. The primary outcomes investigated included the success rate of the procedure, in-hospital mortality, and perioperative complications.

RESULTS

The mean age of the patients was 58.7 ± 12.8 years, with 22.9% being female. The majority of patients (77.1%) presented with aortic stenosis, often accompanied by severe calcification. The medianCPB time was 210 ± 43 min, and the median aortic cross-clamp time was 132 ± 41 min. The procedure was successfully completed in all patients using the endoscopic approach, with no conversions to full sternotomy. Two mortalities were recorded, attributed to postoperative complications including bleeding and cerebral infarctions. The early (30-day) mortality rate was 5.7%. Prolonged mechanical ventilation (>48 h) was required in 17.1% of patients, and reoperation for bleeding was necessary in 2.9% of patients.

CONCLUSIONS

TEAVR is a feasible procedure with the potential to replace the traditional sternotomy approach for aortic valve replacement.

摘要

目的

本研究旨在评估利用三维内镜系统经第四肋间间隙(ICS)的单个工作端口进行全内镜主动脉瓣置换术(TEAVR)的可行性和初步结果。

方法

对2023年12月至2024年6月这六个月期间连续接受TEAVR的35例患者进行了一项回顾性观察研究。患者选择基于单纯主动脉瓣疾病的存在,无需升主动脉置换或主动脉根部扩大。在第四肋间间隙创建一个4厘米的单个工作端口,从右腋中线延伸至腋前线。在右腋前线放置一个用于三维内镜的10毫米套管针。建立外周体外循环(CPB)。研究的主要结果包括手术成功率、住院死亡率和围手术期并发症。

结果

患者的平均年龄为58.7±12.8岁,女性占22.9%。大多数患者(77.1%)表现为主动脉瓣狭窄,常伴有严重钙化。体外循环时间中位数为210±43分钟,主动脉交叉夹闭时间中位数为132±41分钟。所有患者均使用内镜方法成功完成手术,无一例转为全胸骨切开术。记录到两例死亡,归因于术后并发症,包括出血和脑梗死。早期(30天)死亡率为5.7%。17.1%的患者需要延长机械通气(>48小时),2.9%的患者因出血需要再次手术。

结论

TEAVR是一种可行的手术方法,有可能取代传统的胸骨切开术进行主动脉瓣置换。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2234/11496183/fb97ce3d917d/fcvm-11-1468452-g001.jpg

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