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微创主动脉瓣手术:现状与未来方向。

Minimally invasive aortic valve surgery: state of the art and future directions.

作者信息

Glauber Mattia, Ferrarini Matteo, Miceli Antonio

机构信息

Cardiac Surgery and Great Vessels Department, Istituto Clinico Sant'Ambrogio, Gruppo Ospedaliero San Donato, Milan, Italy.

出版信息

Ann Cardiothorac Surg. 2015 Jan;4(1):26-32. doi: 10.3978/j.issn.2225-319X.2015.01.01.

Abstract

Minimally invasive aortic valve replacement (MIAVR) is defined as an aortic valve replacement (AVR) procedure that involves a small chest wall incision as opposed to conventional full sternotomy (FS). The MIAVR approach is increasingly being used with the aim of reducing the "invasiveness" of the surgical procedure, while maintaining the same efficacy, quality and safety of a conventional approach. The most common MIAVR techniques are ministernotomy (MS) and right anterior minithoracotomy (RT) approaches. Compared with conventional surgery, MIAVR has been shown to reduce postoperative mortality and morbidity, providing faster recovery, shorter hospital stay and better cosmetics results, requires less rehabilitations resources and consequently cost reduction. Despite these advantages, MIAVR is limited by the longer cross-clamp and cardiopulmonary bypass (CPB) times, which have raised some concerns in fragile and high risk patients. However, with the introduction of sutureless and fast deployment valves, operative times have dramatically reduced by 35-40%, standardizing this procedure. According to these results, the MIAVR approach using sutureless valves may be the "real alternative" to the transcatheter aortic valve implantation (TAVI) procedures in high risk patients "operable" patients. Prospective randomized trials are required to confirm this hypothesis.

摘要

微创主动脉瓣置换术(MIAVR)被定义为一种主动脉瓣置换(AVR)手术,它采用小胸壁切口,与传统的全胸骨切开术(FS)相对。MIAVR方法的使用越来越广泛,目的是在保持传统方法相同疗效、质量和安全性的同时,降低手术的“侵入性”。最常见的MIAVR技术是微创胸骨切开术(MS)和右前微创胸廓切开术(RT)。与传统手术相比,MIAVR已被证明可降低术后死亡率和发病率,实现更快康复、缩短住院时间并获得更好的美容效果,所需康复资源更少,从而降低成本。尽管有这些优点,但MIAVR受限于较长的主动脉阻断和体外循环(CPB)时间,这在脆弱和高危患者中引发了一些担忧。然而,随着无缝合和快速植入瓣膜的引入,手术时间大幅缩短了35 - 40%,使该手术标准化。根据这些结果,在高危“可手术”患者中,使用无缝合瓣膜的MIAVR方法可能是经导管主动脉瓣植入术(TAVI)的“真正替代方案”。需要进行前瞻性随机试验来证实这一假设。

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