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[一例伴有全身受累的颅面部骨髓炎患者:病例报告]

[Craniofacial osteomyelitis in a patient with systemic involvement: a case report].

作者信息

Serpa-Romero Xiomara Zilena, Guzmán-Maciel Gustavo Julio, Montes-García Raúl, Romo-Pérez Camilo A

机构信息

Facultad de Odontología, Universidad del Magdalena. Santa Marta, Colombia.

Departamento Cirugía Maxilofacial. Clínica Mar Caribe, Santa Marta, Colombia.

出版信息

Rev Cient Odontol (Lima). 2024 Sep 17;12(3):e213. doi: 10.21142/2523-2754-1203-2024-213. eCollection 2024 Jul-Sep.

DOI:10.21142/2523-2754-1203-2024-213
PMID:39444725
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11495174/
Abstract

This report presents the case of a 61-year-old male patient with diabetes, hypertension, and a history of severe COVID-19 with osteomyelitis of the frontal sinus and upper jaw. The patient reported intense pain in the facial and maxillary area for two months. The computed tomography images showed mucoperiosteal thickening of the maxillary sinus and the magnetic resonance imaging showed multiple lytic lesions at the frontal sinus level, as well as brain abscesses in the left frontal region that were correlated with the microbiological cultures. In the intraoral clinical examination, segments with a necrotic appearance of the upper jaw, orosinusal fistula and multiple dental infectious foci were observed. The patient was treated with antibiotics, analgesics, anti-inflammatories, insulin, and proton pump inhibitor. Trephination of the frontal sinus, drainage of the abscess and sequestrectomy in the maxilla were performed and sessions with a hyperbaric chamber were ordered.

摘要

本报告介绍了一名61岁男性患者的病例,该患者患有糖尿病、高血压,有严重新冠病毒病病史,并发额窦和上颌骨髓炎。患者自述面部和上颌区域剧烈疼痛两个月。计算机断层扫描图像显示上颌窦黏膜骨膜增厚,磁共振成像显示额窦水平有多个溶骨性病变,以及左额叶区域的脑脓肿,这些与微生物培养结果相关。在口腔临床检查中,观察到上颌有坏死外观的节段、口鼻窦瘘和多个牙齿感染灶。患者接受了抗生素、镇痛药、抗炎药、胰岛素和质子泵抑制剂治疗。进行了额窦环钻术、脓肿引流和上颌骨死骨切除术,并安排了高压氧舱治疗疗程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/2713e53aa348/odontologica-12-03-e213-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/11c30128d31f/odontologica-12-03-e213-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/9182c996bb5a/odontologica-12-03-e213-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/2713e53aa348/odontologica-12-03-e213-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/11c30128d31f/odontologica-12-03-e213-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/9182c996bb5a/odontologica-12-03-e213-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf84/11495174/2713e53aa348/odontologica-12-03-e213-gf3.jpg

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本文引用的文献

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Maxillary mucormycosis and concurrent osteomyelitis in a post-COVID-19 patient with new onset diabetes mellitus.一名新冠后新发糖尿病患者的上颌毛霉菌病并发骨髓炎
Proc (Bayl Univ Med Cent). 2023 Feb 23;36(3):389-391. doi: 10.1080/08998280.2023.2177081. eCollection 2023.
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Management of frontal sinus fungal osteomyelitis in the COVID 19 era: A case series.COVID-19 时代额窦真菌性骨髓炎的治疗:病例系列。
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Case of maxillary actinomycotic osteomyelitis, a rare post COVID complication-case report.
上颌放线菌性骨髓炎病例,一种罕见的新冠后并发症——病例报告
Ann Med Surg (Lond). 2022 Aug;80:104242. doi: 10.1016/j.amsu.2022.104242. Epub 2022 Jul 31.
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Post-COVID-19 related osteonecrosis of the jaw (PC-RONJ): an alarming morbidity in COVID-19 surviving patients.COVID-19 相关颌骨坏死(PC-RONJ):COVID-19 幸存患者中令人震惊的发病率。
BMC Infect Dis. 2022 Jun 14;22(1):544. doi: 10.1186/s12879-022-07518-9.
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Mixed Infections (Mucormycosis, Actinomycosis and Candidiasis) Leading to Maxillary Osteomyelitis in a Diabetic Mellitus Patient in Post COVID Phase: First Case Report.混合感染(毛霉病、放线菌病和念珠菌病)导致 COVID 后阶段糖尿病患者上颌骨骨髓炎:首例病例报告。
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Covid-19-associated fungal osteomyelitis of jaws and sinuses: An experience-driven management protocol.COVID-19 相关的颌骨和鼻窦真菌性骨髓炎:基于经验的治疗方案。
Med Mycol. 2022 Feb 2;60(2). doi: 10.1093/mmy/myab082.
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