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抗坏血酸过氧化物酶相关蛋白:对其在衣藻和拟南芥中功能的见解

The ascorbate peroxidase-related protein: insights into its functioning in Chlamydomonas and Arabidopsis.

作者信息

Caccamo Anna, Lazzarotto Fernanda, Margis-Pinheiro Marcia, Messens Joris, Remacle Claire

机构信息

Genetics and Physiology of Microalgae, InBios/Phytosystems Research Unit, University of Liège, Liège, Belgium.

Redox Signaling Lab, VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.

出版信息

Front Plant Sci. 2024 Oct 9;15:1487328. doi: 10.3389/fpls.2024.1487328. eCollection 2024.

Abstract

We review the newly classified ascorbate peroxidase-related (APX-R) proteins, which do not use ascorbate as electron donor to scavenge HO. We summarize recent discoveries on the function and the characterization of the APX-R protein of the green unicellular alga and the land plant . Additionally, we conduct analyses on the conserved MxxM motif, present in most of the APX-R protein in different organisms, which is proposed to bind copper. Based on these analyses, we discuss the similarities between the APX-R and the class III peroxidases.

摘要

我们综述了新分类的抗坏血酸过氧化物酶相关(APX-R)蛋白,这些蛋白不使用抗坏血酸作为电子供体来清除羟基自由基。我们总结了关于绿色单细胞藻类和陆地植物中APX-R蛋白功能及特性的最新发现。此外,我们对不同生物体中大多数APX-R蛋白所具有的保守MxxM基序进行了分析,该基序被认为可结合铜。基于这些分析,我们讨论了APX-R与III类过氧化物酶之间的相似性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cae/11496181/f207aab614e5/fpls-15-1487328-g001.jpg

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