Tian Yue, Ao Yong-Qin, Xiong Yu-Ling, Huang Chun-Xia, Jin Xin, Liu Li-Shuang
Gastroenterology, Fengdu People's Hospital, China.
Pathology, Fengdu People's Hospital.
Rev Esp Enferm Dig. 2025 Mar;117(3):172-173. doi: 10.17235/reed.2024.10851/2024.
Malignant melanoma (MM) is a common and highly invasive malignant tumor in clinical practice that is prone to occur in the skin and mucosa and prone to early metastasis. The common sites of metastasis are the liver, lungs, brain, etc. Metastatic gastrointestinal mucosa is relatively rare. Once metastasis occurs, the prognosis of patients is significantly worse. This article reports a case diagnosed as MM with liver, stomach, and duodenal metastasis by ultrasound-guided endoscopic puncture at Fengdu People's Hospital in Chongqing, with gastrointestinal discomfort as the initial symptom and a history of melanoma. Therefore, when a patient has a history of melanoma surgery and presents with digestive symptoms, it is necessary to consider the disease. Regular endoscopic screening should be performed, and early surgical treatment and postoperative chemotherapy combined with targeted therapy may improve patient prognosis and prolong patient survival.
恶性黑色素瘤（MM）是临床实践中一种常见且侵袭性很强的恶性肿瘤，易发生于皮肤和黏膜，且易于早期转移。常见的转移部位有肝脏、肺、脑等。转移性胃肠道黏膜相对少见。一旦发生转移，患者的预后会明显变差。本文报道了1例在重庆丰都县人民医院经超声引导下内镜穿刺诊断为MM并伴有肝脏、胃和十二指肠转移的病例，该患者以胃肠道不适为首发症状，且有黑色素瘤病史。因此，当患者有黑色素瘤手术史并出现消化道症状时，有必要考虑该病。应定期进行内镜筛查，早期手术治疗及术后化疗联合靶向治疗可能改善患者预后并延长患者生存期。
