Chahure Shreya, De La Revilla Negro Juan, Sharip Mohmmed, Chan James
Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
BMJ Case Rep. 2025 Mar 27;18(3):e262631. doi: 10.1136/bcr-2024-262631.
This case report details two instances of gastrointestinal (GI) involvement in metastatic melanoma. The first patient, a man in his mid-70s with a history of melanoma and recent brain metastases, presented with melaena and was found to have metastatic lesions in the stomach and duodenum. The second patient, a man in his late 50s with a history of chest wall melanoma, presented with complex GI symptoms and was discovered to have a metastatic melanoma lesion at the gastro-oesophageal junction. Both cases highlight the importance of maintaining a high degree of suspicion for GI metastasis from melanoma in patients presenting with GI symptoms, emphasising timely endoscopic evaluation and biopsy for accurate diagnosis and management.
本病例报告详细介绍了转移性黑色素瘤累及胃肠道（GI）的两个实例。首例患者为一名70多岁的男性，有黑色素瘤病史且近期发生脑转移，出现黑便，经检查发现胃和十二指肠有转移病灶。第二例患者为一名50多岁的男性，有胸壁黑色素瘤病史，出现复杂的胃肠道症状，经检查发现胃食管交界处有转移性黑色素瘤病灶。这两例病例均强调，对于出现胃肠道症状的患者，高度怀疑黑色素瘤发生胃肠道转移至关重要，强调应及时进行内镜评估和活检，以实现准确诊断和治疗。
