Wang Zi, Dai Zhuozhi, Zhou Xinyi, Dai Jiankun, Ge Yuxi, Hu Shudong
Department of Radiology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Department of Radiology, Shantou Central Hospital, Shantou, Guangdong, China.
Insights Imaging. 2024 Oct 24;15(1):256. doi: 10.1186/s13244-024-01796-4.
To assess the image quality of synthetic double inversion recovery (SyDIR) imaging and enhance the value of T2-weighted imaging (T2WI) in evaluating T stage for rectal cancer patients.
A total of 112 pathologically confirmed rectal cancer patients were retrospectively selected after undergoing MRI, including synthetic MRI. The image quality of T2WI and SyDIR imaging was compared based on signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), overall picture quality, presence of motion artifacts, lesion edge sharpness, and conspicuity. The concordance between MRI and pathological staging results, using T2WI alone and the combination of T2WI and SyDIR for junior and senior radiologists, was assessed using the Kappa test. The area under the receiver operating characteristic curve (AUC) was used to assess the diagnostic efficacy of extramural infiltration in rectal cancer patients.
No significant differences in imaging quality were observed between conventional T2WI and SyDIR (p = 0.07-0.53). The combination of T2WI and SyDIR notably improved the staging concordance between MRI and pathology for both junior (kappa value from 0.547 to 0.780) and senior radiologists (kappa value from 0.738 to 0.834). In addition, the integration of T2WI and SyDIR increased the AUC for diagnosing extramural infiltration for both junior (from 0.842 to 0.918) and senior radiologists (from 0.917 to 0.938).
The combination of T2WI and SyDIR increased the consistency of T staging between MRI and pathology, as well as the diagnostic performance of extramural infiltration, which would benefit treatment selection.
SyDIR sequence provides additional diagnostic value for T2WI in the T staging of rectal cancer, improving the agreement of T staging between MRI and pathology, as well as the diagnostic performance of extramural infiltration.
Synthetic double inversion recovery (SyDIR) and T2WI have comparable image quality. SyDIR provides rectal cancer anatomical features for extramural infiltration detections. The combination of T2WI and SyDIR improves the accuracy of T staging in rectal cancer.
评估合成双反转恢复（SyDIR）成像的图像质量，并提高T2加权成像（T2WI）在评估直肠癌患者T分期中的价值。
回顾性选取112例经病理证实的直肠癌患者，这些患者均接受了包括合成磁共振成像在内的MRI检查。基于信噪比（SNR）、对比噪声比（CNR）、整体图像质量、运动伪影的存在、病变边缘清晰度和可见性，比较T2WI和SyDIR成像的图像质量。使用Kappa检验评估初级和高级放射科医生单独使用T2WI以及联合使用T2WI和SyDIR时MRI与病理分期结果之间的一致性。采用受试者工作特征曲线下面积（AUC）评估直肠癌患者壁外浸润的诊断效能。
常规T2WI和SyDIR之间在成像质量上未观察到显著差异（p = 0.07 - 0.53）。T2WI和SyDIR的联合显著提高了初级（kappa值从0.547提高到0.780）和高级放射科医生（kappa值从0.738提高到0.834）MRI与病理之间的分期一致性。此外，T2WI和SyDIR的联合提高了初级（从0.842提高到0.918）和高级放射科医生（从0.917提高到0.938）诊断壁外浸润的AUC。
T2WI和SyDIR的联合提高了MRI与病理之间T分期的一致性以及壁外浸润的诊断性能，这将有利于治疗选择。
SyDIR序列为T2WI在直肠癌T分期中提供了额外的诊断价值，提高了MRI与病理之间T分期的一致性以及壁外浸润的诊断性能。
合成双反转恢复（SyDIR）和T2WI具有可比的图像质量。SyDIR为壁外浸润检测提供直肠癌解剖特征。T2WI和SyDIR的联合提高了直肠癌T分期的准确性。
