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新冠疫情大流行期间西班牙加那利群岛的“Patera 综合征”。

'Patera syndrome' during the COVID-19 pandemic in the Canary Islands (Spain).

机构信息

Unit of Infectious Diseases and Tropical Medicine, University Insular Hospital of Gran Canaria and Department of Medical & Surgical Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.

Unit of Infectious Diseases and Tropical Medicine, University Insular Hospital of Gran Canaria, Las Palmas de Gran Canaria, Spain.

出版信息

PLoS One. 2024 Oct 24;19(10):e0312355. doi: 10.1371/journal.pone.0312355. eCollection 2024.

DOI:10.1371/journal.pone.0312355
PMID:39446793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11500946/
Abstract

BACKGROUND

The number of migrants arriving on the shores of the Canary Islands continues to increase. The conditions under which the crossing is made, in small crowded, unsanitary boats (pateras or cayucos), have many and significant health problems.

OBJECTIVE

To describe the demographic, clinical, microbiological characteristics and evolution of a series of patients who recently arrived by patera and required hospitalization.

PATIENTS AND METHODS

This observational, cross-sectional, and retrospective study included all patients newly arrived in Gran Canaria (Spain) by patera or cayuco from 2020 to 2022. Acute patera syndrome (APS) was defined as one or more of the following: dehydration, hypothermia, shock or rhabdomyolysis. Skin and soft tissue or musculoskeletal patera syndrome (SSTMSPS) was defined as conditions characterized by lesions of the skin, subcutaneous tissue, bone, or joint, excluding superficial erosions.

RESULTS

During the study period, 193 migrants were admitted, mostly males with a median age of 23 years from West Africa. A total of 36.99% presented with APS with a single diagnostic criterion (most commonly dehydration, 86.9%), 11.56% with SSTMPS and 51.44% with both syndromes. A total of 109 patients presented with SSTMSPS, the most common being lower extremity ulcers. The most frequently isolated microorganisms were gram-negative (i.e. Shewanella algae). The McMahon score effectively predicted the need for renal replacement therapy in cases of rhabdomyolysis. Twenty patients presented with pneumomediastinum, which was benign. SARS-CoV-2 infection was not a problem in any of them. Surgical intervention was required in 22% of cases, including 8 amputations, all of which were minor. No patient died during admission.

CONCLUSION

Patera syndrome has specific characteristics that should be identified promptly to initiate the most effective treatment for optimal outcomes.

摘要

背景

抵达加那利群岛海岸的移民人数持续增加。穿越小船(pateras 或 cayucos)的条件很差,小船拥挤、不卫生,这导致了许多严重的健康问题。

目的

描述一组最近乘坐 patera 抵达并需要住院治疗的患者的人口统计学、临床、微生物学特征和演变。

患者和方法

这是一项观察性、横断面和回顾性研究,纳入了 2020 年至 2022 年期间所有从 patera 或 cayucos 抵达大加那利岛(西班牙)的新移民患者。急性 patera 综合征(APS)定义为以下一种或多种情况:脱水、低体温、休克或横纹肌溶解。皮肤和软组织或肌肉骨骼 patera 综合征(SSTMSPS)定义为以皮肤、皮下组织、骨骼或关节病变为特征的疾病,不包括浅表糜烂。

结果

研究期间,共收治 193 名移民,主要为来自西非的男性,中位年龄为 23 岁。共有 36.99%的患者出现 APS,仅有一个诊断标准(最常见的是脱水,占 86.9%),11.56%的患者出现 SSTMPS,51.44%的患者同时出现两种综合征。共有 109 例患者出现 SSTMSPS,最常见的是下肢溃疡。最常分离的微生物是革兰氏阴性菌(即海藻希瓦氏菌)。McMahon 评分能有效地预测横纹肌溶解症患者是否需要肾脏替代治疗。20 例患者出现良性纵隔气肿。他们中没有人感染 SARS-CoV-2。22%的患者需要手术干预,包括 8 例截肢,均为小截肢。住院期间无患者死亡。

结论

patera 综合征具有特定的特征,应迅速识别这些特征,以便为患者提供最佳结局的最有效治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af23/11500946/cbd1da281081/pone.0312355.g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af23/11500946/cbd1da281081/pone.0312355.g005.jpg

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