Prasad R Senthil, Koshy Tony A, Sankarananthan R, Balakrishnan Logesh, Nagu Kamatchi, Shekhar Madhu
Department of Cataract and IOL Services, Aravind Eye Hospital and Post Graduate Institue of Ophthalmology, Madurai, Tamil Nadu, India.
Indian J Ophthalmol. 2025 Mar 1;73(3):370-376. doi: 10.4103/IJO.IJO_3162_23. Epub 2024 Oct 25.
To evaluate higher order aberrations (HOA) in different types of posterior capsule opacification (PCO) and analyze its changes following Nd:YAG laser posterior capsulotomy (LPC).
Tertiary care ophthalmic hospital.
Prospective, comparative, observational study.
One hundred ninety-three pseudophakic eyes with PCO were evaluated over 3 months. PCO was classified into pearly, fibrous, and mixed types. Their uncorrected visual acuity (UCVA), corrected distance visual acuity (CDVA), intraocular pressure (IOP), evaluation of posterior capsule opacification (EPCO) scoring and root mean square values of HOA (total, coma, spherical, and trefoil) were measured using a wavefront aberrometer before and after LPC.
Pearly, fibrous, and mixed PCO were observed in 89 (46.1%), 47 (24.4%), and 57 (29.5%) eyes respectively. The UCVA and CDVA showed improvement in all types of PCO post-procedure. The total HOA was 0.48 ± 0.47, 0.43 ± 0.42, 0.37 ± 0.34, and 0.76 ± 0.53, the coma aberrations were 0.18 ± 0.15, 0.18 ± 0.14, and 0.19 ± 0.19, spherical aberrations were 0.07 ± 0.12, 0.09 ± 0.12, and 0.05 ± 0.06, whereas the trefoil aberrations were 0.35 ± 0.44, 0.24 ± 0.26, and 0.21 ± 0.20, 15-day post-Nd:YAG LPC in pearly, fibrous, and mixed PCO respectively, all of which showed a significant reduction. The EPCO score showed no significant difference between different subtypes of PCO and had no correlation with the HOA.
Post Nd:YAG LPC showed improvement in visual acuity with significant reduction in HOA in all types of PCO.
评估不同类型后囊膜混浊（PCO）的高阶像差（HOA），并分析钕钇铝石榴石激光后囊膜切开术（LPC）后其变化情况。
三级眼科专科医院。
前瞻性、对比性、观察性研究。
在3个月内对193只患有PCO的人工晶状体眼进行评估。PCO分为珍珠样、纤维样和混合型。在LPC前后，使用波前像差仪测量其未矫正视力（UCVA）、矫正远视力（CDVA）、眼压（IOP）、后囊膜混浊评估（EPCO）评分以及HOA的均方根值（总和、彗差、球差和三叶草像差）。
分别在89只（46.1%）、47只（24.4%）和57只（29.5%）眼中观察到珍珠样、纤维样和混合型PCO。术后所有类型的PCO的UCVA和CDVA均有所改善。珍珠样、纤维样和混合型PCO在钕钇铝石榴石激光LPC术后15天的总HOA分别为0.48±0.47、0.43±0.42、0.37±0.34和0.76±0.53，彗差分别为0.18±0.15、0.18±0.14和0.19±0.19，球差分别为0.07±0.12、0.09±0.12和0.05±0.06，而三叶草像差分别为0.35±0.44、0.24±0.26和0.21±0.20，所有这些均显示出显著降低。EPCO评分在PCO的不同亚型之间无显著差异，且与HOA无相关性。
钕钇铝石榴石激光LPC术后，所有类型的PCO的视力均有改善，HOA显著降低。
