Gupta Chhavi, Patidar Narendra, Gaikwad Himanshu, Mishra Mihir, Das Sima
Oculoplasty and Ocular Oncology, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Oculoplasty Subgroup, Bodhya Eye Consortium, India.
Indian J Ophthalmol. 2025 Feb 1;73(2):253-260. doi: 10.4103/IJO.IJO_786_24. Epub 2024 Oct 25.
To describe the epidemiological profile and clinical characteristics of ocular and periocular tumors in patients presenting to three tertiary care referral centers in North and Central India.
Hospital-based consortium study.
Retrospective, descriptive, observational study.
A total of 3184 patients were diagnosed with 3557 ocular and periocular tumors over 11 years from 2010 to 2021. Of these, 2395 (67.33%) were benign, 84 (2.36%) were premalignant, and 1078 (30.30%) were malignant. The most common location was the ocular surface (n = 1294, 37.09%), followed by the eyelid (n = 1185, 33.97%), intraocular (n = 624, 17.88%), and orbit (n = 454, 13.01%). The most common tumors were retinoblastoma (n = 483, 13.57%), ocular surface squamous neoplasia (OSSN) (n = 301, 8.46%), and dermoid cyst (n = 167, 4.69%). In the pediatric age group, retinoblastoma was the most common tumor (n = 483, 13.57%), while in adults, it was OSSN (n = 301, 8.46%). The stage at presentation for malignant tumors was divided into in-situ (57.14%), local spread (8.16%), and metastasis (32.83%). For specific tumor locations, the stages were 78.83%, 17.51%, and 2.18%, respectively, for eyelid tumors; 51.76%, 27.05%, and 17.64%, respectively, for orbital tumors; 88.37%, 5.81%, and 5.19%, respectively for ocular surface tumors; and 35.71%, 14.15%, and 50.28%, respectively, for intraocular tumors.
Identifying the epidemiological characteristics of ocular and periocular tumors will aid in early diagnosis and timely intervention. Intraocular tumors showed delayed diagnosis, advanced stages at presentation, and required patients to travel longer distances for treatment, indicating the need for strengthened diagnostic and treatment facilities to improve access to care.
描述印度北部和中部三家三级医疗转诊中心就诊患者眼部及眼周肿瘤的流行病学概况和临床特征。
基于医院的联合研究。
回顾性、描述性、观察性研究。
在2010年至2021年的11年中，共有3184例患者被诊断出患有3557例眼部及眼周肿瘤。其中，2395例（67.33%）为良性，84例（2.36%）为癌前病变，1078例（30.30%）为恶性。最常见的部位是眼表（n = 1294，37.09%），其次是眼睑（n = 1185，33.97%）、眼内（n = 624，17.88%）和眼眶（n = 454，13.01%）。最常见的肿瘤是视网膜母细胞瘤（n = 483，13.57%）、眼表鳞状上皮瘤（OSSN）（n = 301，8.46%）和皮样囊肿（n = 167，4.69%）。在儿童年龄组中，视网膜母细胞瘤是最常见的肿瘤（n = 483，13.57%），而在成人中，是OSSN（n = 301，8.46%）。恶性肿瘤就诊时的分期分为原位癌（57.14%）、局部扩散（8.16%）和转移（32.83%）。对于特定的肿瘤部位，眼睑肿瘤的分期分别为78.83%、17.51%和2.18%；眼眶肿瘤分别为51.76%、27.05%和17.64%；眼表肿瘤分别为88.37%、5.81%和5.19%；眼内肿瘤分别为35.71%、14.15%和50.28%。
确定眼部及眼周肿瘤的流行病学特征将有助于早期诊断和及时干预。眼内肿瘤显示诊断延迟、就诊时分期较晚，且患者需要长途跋涉进行治疗，这表明需要加强诊断和治疗设施，以改善医疗服务的可及性。
