Guy's & St Thomas' Oesophago-gastric Centre, London, UK.
Regional Oesophago-gastric Unit, Royal Surrey County Hospital, Guildford, UK.
Br J Surg. 2024 Oct 1;111(10). doi: 10.1093/bjs/znae223.
Prehabilitation is safe, feasible and may improve a range of outcomes in patients with oesophago-gastric cancer (OGC). Recent studies have suggested the potential of prehabilitation to improve body composition, sarcopenia and physical fitness, reduce surgical complications and improve quality of life. Despite this, prehabilitation services are not offered throughout all OGC centres in the UK. Where prehabilitation is offered, delivery and definitions vary significantly, as do funding sources and access.
A professional association endorsed series of consensus meetings were conducted using a modified Delphi process developed by the Peri-Operative Quality Initiative (POQI) to identify and refine consensus statements relating to the development and delivery of prehabilitation services for OGC patients. Participants from a variety of disciplines were identified based on a track record of published studies in the field of prehabilitation and/or practice experience encompassing prehabilitation of OGC patients. Approval from the POQI board was obtained and independent supervision provided by POQI.
A total of 20 statements were developed and agreed by 26 participants over a preliminary meeting and 2 semi-structured formal POQI meetings. Ten research themes were identified. In the case of one statement, consensus was not reached and the statement was recorded and developed into a research theme. A strong recommendation was made for the majority of the consensus statements (17 of 20).
Consensus statements encompassing the interventions and outcomes of prehabilitation services in oesophago-gastric cancer surgery have been developed to inform the implementation of programmes.
术前康复在治疗食管胃结合部癌症(OGC)患者方面安全、可行,并且可能改善多种结局。最近的研究表明,术前康复具有改善身体成分、减少肌肉减少症和提高体能、降低手术并发症和提高生活质量的潜力。尽管如此,英国并非所有的 OGC 中心都提供术前康复服务。在提供术前康复的地方,其实施和定义差异很大,资金来源和途径也不同。
采用经过改良的围手术期质量倡议(POQI)德尔菲法,由专业协会认可的一系列共识会议,确定并完善与 OGC 患者术前康复服务的发展和实施相关的共识声明。根据在术前康复领域发表研究或实践经验(包括 OGC 患者术前康复)的记录,确定了来自不同学科的参与者。POQI 委员会已批准,并由 POQI 进行独立监督。
在初步会议和 2 次半结构化的 POQI 正式会议上,共有 26 名参与者提出并达成了 20 项声明。确定了 10 个研究主题。对于一项声明,未达成共识,该声明被记录下来并发展成为一个研究主题。大多数共识声明(20 项中的 17 项)都得到了强烈推荐。
已经制定了包含食管胃结合部癌症手术术前康复服务干预措施和结局的共识声明,旨在为方案的实施提供信息。