Emerg Infect Dis. 2024 Nov;30(11):2261-2270. doi: 10.3201/eid3011.240329.
Limited data exist on mortality rates after tuberculosis (TB) treatment in the United States. We analyzed mortality rates for all adults in Georgia, USA, who had a TB diagnosis and finished treatment during January 1, 2008-December 31, 2019. We obtained posttreatment mortality rate data from the National Death Index and calculated standardized mortality ratios (SMRs) for TB treatment survivors and the general Georgia population. Among 3,182 TB treatment survivors, 233 (7.3%) had died as of December 31, 2019. The overall TB cohort age- and sex-adjusted SMR was 0.89 (95% CI 0.73-1.05). The SMR among US-born TB treatment survivors was 1.56 (95% CI 1.36-1.77). In the TB cohort, US-born status, HIV co-infection, excess alcohol use, diabetes mellitus, and end-stage renal disease were associated with increased risk for death after TB treatment. TB treatment survivors could benefit from improved linkage to primary and HIV comprehensive care to prevent posttreatment death.
关于美国结核病（TB）治疗后的死亡率，现有数据有限。我们分析了美国佐治亚州所有在 2008 年 1 月 1 日至 2019 年 12 月 31 日期间接受 TB 诊断并完成治疗的成年人的死亡率。我们从国家死亡指数获得了治疗后死亡率数据，并计算了 TB 治疗幸存者和佐治亚州普通人群的标准化死亡率比（SMR）。在 3182 名 TB 治疗幸存者中，截至 2019 年 12 月 31 日，已有 233 人（7.3%）死亡。总体 TB 队列的年龄和性别调整 SMR 为 0.89（95%CI 0.73-1.05）。在美国出生的 TB 治疗幸存者的 SMR 为 1.56（95%CI 1.36-1.77）。在 TB 队列中，美国出生、HIV 合并感染、过量饮酒、糖尿病和终末期肾病与 TB 治疗后死亡风险增加相关。TB 治疗幸存者可以从改善与初级保健和 HIV 综合护理的联系中受益，以预防治疗后死亡。
