Dipalma Gianna, Inchingolo Angelo Michele, Trilli Irma, Ferrante Laura, Noia Angela Di, de Ruvo Elisabetta, Inchingolo Francesco, Mancini Antonio, Cocis Stefan, Palermo Andrea, Inchingolo Alessio Danilo
Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy.
Maxillo-Facial Surgery, Interdisciplinary Department of Medicine, University of Bari, 70100 Bari, Italy.
Diagnostics (Basel). 2025 Jan 16;15(2):194. doi: 10.3390/diagnostics15020194.
This study aims to evaluate the management of oro-antral communications (OAC) and fistulas (OAF), focusing on treatment strategies based on defect size, epithelialization, and the presence of sinus infections, while exploring both traditional and emerging techniques. The systematic review was conducted following the PRISMA guidelines and registered on PROSPERO (CDR ID 623251). Using targeted keywords, articles in English published within the last 10 years were analyzed from databases such as PubMed, WoS and Scopus, selecting only clinical studies on human patients. After thorough screening, 20 publications were included in the qualitative analysis, among 734 initially identified. Small OACs (<5 mm) were managed conservatively with hemostatic materials, while larger defects (>5 mm) required surgical closure, with the Bichat flap proving highly effective for large defects. Innovative treatments using autologous bone grafts and PRF showed promise in supporting tissue regeneration. In cases with sinusitis, the combination of FESS and intra-oral closure techniques resulted in high success rates for infection resolution and defect closure. Treatment outcomes for OAC and OAF are highly dependent on the size of the defect and the presence of sinusitis. Multidisciplinary collaboration, along with timely surgical intervention and adherence to medical therapies, is essential for successful management. Emerging techniques and minimally invasive procedures continue to improve patient outcomes, offering hope for more effective and sustainable solutions in complex cases.
本研究旨在评估口腔上颌窦交通(OAC)和瘘管(OAF)的处理方法,重点关注基于缺损大小、上皮化以及鼻窦感染情况的治疗策略,同时探索传统技术和新兴技术。本系统评价按照PRISMA指南进行,并在PROSPERO(CDR ID 623251)上进行了注册。使用目标关键词,从PubMed、WoS和Scopus等数据库中分析过去10年内发表的英文文章,仅选择关于人类患者的临床研究。经过全面筛选,在最初确定的734篇文章中,有20篇被纳入定性分析。小型OAC(<5 mm)采用止血材料进行保守处理,而较大的缺损(>5 mm)则需要手术闭合,比沙氏瓣被证明对大缺损非常有效。使用自体骨移植和富血小板纤维蛋白的创新治疗方法在支持组织再生方面显示出前景。对于鼻窦炎患者,功能性内镜鼻窦手术(FESS)与口腔内闭合技术相结合,在解决感染和闭合缺损方面成功率很高。OAC和OAF的治疗结果高度依赖于缺损大小和鼻窦炎的存在情况。多学科协作,以及及时的手术干预和坚持药物治疗,对于成功处理至关重要。新兴技术和微创手术不断改善患者预后,为复杂病例提供了更有效和可持续解决方案的希望。