骨折风险评估工具的最新进展：15 年多来我们有哪些新的认识？
An Update on the Fracture Risk Assessment Tool: What Have We Learned over 15+ years?
机构信息
Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, The University of Chicago, 5841 South Maryland Avenue, MC 1027, Chicago, IL 60637, USA.
Department of Medicine, Section of Endocrinology, Diabetes, and Metabolism, The University of Chicago, 5841 South Maryland Avenue, MC 1027, Chicago, IL 60637, USA.
出版信息
Endocrinol Metab Clin North Am. 2024 Dec;53(4):531-545. doi: 10.1016/j.ecl.2024.08.001. Epub 2024 Sep 10.
The Fracture Risk Assessment Tool (FRAX) was launched in 2008 and uses clinical variables to estimate 10-year fracture risk. FRAX has been incorporated into clinical treatment guidelines and is well validated in specific disease states like chronic kidney disease. However, there are risk factors which are not captured by FRAX such as diabetes and falls. The use of race-ethnicity as a factor in FRAX is a source of controversy. Though other risk calculators exist, FRAX is likely to remain the gold standard for fracture risk prediction. An update of FRAX using data from a larger cohort is in development.
骨折风险评估工具（FRAX）于 2008 年推出，它使用临床变量来估计 10 年骨折风险。FRAX 已被纳入临床治疗指南，并在慢性肾脏病等特定疾病状态下得到了很好的验证。然而，FRAX 并未涵盖一些风险因素，如糖尿病和跌倒。种族作为 FRAX 的一个因素是有争议的。虽然存在其他风险计算器，但 FRAX 可能仍然是骨折风险预测的黄金标准。正在开发使用更大队列数据更新的 FRAX。
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