Zhang Yujie, Liu Hui, Feng Chaochen, Yang Yadi, Cui Liwei
School of Humanities and Management, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Department of Quality Management, Jining N0.1 People's Hospital, Jining, Shandong, China.
Front Psychiatry. 2024 Oct 9;15:1405320. doi: 10.3389/fpsyt.2024.1405320. eCollection 2024.
This study systematically analyzes the prevalence of sleep disturbance in patients with endometriosis.
The PubMed, Web of Science, Embase, Wanfang, China National Knowledge Internet Database (CNKI), China Science and Technology Journal Database were searched from their establishment to January 2024, using the search terms endometriosis and sleep disturbance to collect relevant literature on the prevalence of sleep disturbance in patients with endometriosis. Two researchers independently screened the literature, extracted data, and evaluated the risk of bias. The prevalence of sleep disorders in patients with endometriosis was systematically analyzed using Stata17.0 software.
Sixteen studies with 2573 participants were included. The prevalence of sleep disturbance in patients with endometriosis was 70.8% (95% confidence interval: 60.7%~80.9%). The said prevalence was higher in China than in Iran and the European countries (78.2 vs. 57.6 vs. 64.4, =9.27, =0.010) and increased significantly since 2018 (79.0 vs. 61.3, =3.97, =0.046). This prevalence was significantly higher in the cohort study than that in cross-sectional and case-control studies (84.0 vs. 74.0 vs. 59.5, =7.16, =0.028).
The prevalence of sleep disturbance is high in patients with endometriosis, particularly in China and its prevalence has increased significantly in recent years. Appropriate interventions are recommended to effectively prevent or minimize sleep disturbances in patients with endometriosis.
本研究系统分析子宫内膜异位症患者睡眠障碍的患病率。
检索PubMed、Web of Science、Embase、万方、中国知网数据库（CNKI）、中国科技期刊数据库自建库至2024年1月，使用检索词“子宫内膜异位症”和“睡眠障碍”收集有关子宫内膜异位症患者睡眠障碍患病率的相关文献。两名研究人员独立筛选文献、提取数据并评估偏倚风险。使用Stata17.0软件对子宫内膜异位症患者睡眠障碍的患病率进行系统分析。
纳入16项研究，共2573名参与者。子宫内膜异位症患者睡眠障碍的患病率为70.8%（95%置信区间：60.7%~80.9%）。该患病率在中国高于伊朗和欧洲国家（78.2对57.6对64.4，χ² = 9.27，P = 0.010），且自2018年以来显著上升（79.0对61.3，χ² = 3.97，P = 0.046）。队列研究中的患病率显著高于横断面研究和病例对照研究（84.0对74.0对59.5，χ² = 7.16，P = 0.028）。
子宫内膜异位症患者睡眠障碍的患病率较高，尤其是在中国，且近年来其患病率显著上升。建议采取适当干预措施，有效预防或尽量减少子宫内膜异位症患者的睡眠障碍。
