Ramasubramanian Darshan, Hernández-Verdejo José Luis, López-Alonso José Manuel
Faculty of Optics and Optometry, Complutense University of Madrid, Arcos de Jalón 118, 28037 Madrid, Spain.
Alain Afflelou Óptico Portugal, Av. António Augusto de Aguiar 11, 1050-016 Lisbon, Portugal.
Bioengineering (Basel). 2024 Sep 27;11(10):966. doi: 10.3390/bioengineering11100966.
This study presents a finite element analysis to model ocular biomechanics and the interactions between the human eye and contact lenses in the closed-eye condition. The closed-eye state, where the eyelids are fully shut, presents challenges for experimental measurements due to the invasive nature of accessing and analysing the contact lens and corneal interface, making simulation tools valuable for accurate characterisation. The primary objective of this study was to examine how CLs fold and twist and their impact on the cornea when the eye is closed. The secondary aim of this study was to assess how crucial contact lens parameters (Young's modulus, base curve, and diameter) influence corneal stress distribution and the overall fit of the lens on the eye. The findings show that increasing Young's modulus significantly reduces corneal stress and promotes uniform stress distribution, making it the most influential factor for wearer comfort and safety. While base curve and diameter variations primarily affect contact area, their impact on stress distribution is minimal. This research provides insights for improving contact lens design and enhancing safety for contact lens wearers.
本研究提出了一种有限元分析方法，用于模拟闭眼状态下的眼部生物力学以及人眼与隐形眼镜之间的相互作用。在闭眼状态下，眼睑完全闭合，由于获取和分析隐形眼镜与角膜界面具有侵入性，这给实验测量带来了挑战，因此模拟工具对于准确表征非常有价值。本研究的主要目的是研究闭眼时隐形眼镜如何折叠和扭曲及其对角膜的影响。本研究的次要目的是评估关键的隐形眼镜参数（杨氏模量、基弧和直径）如何影响角膜应力分布以及镜片在眼睛上的整体贴合度。研究结果表明，增加杨氏模量可显著降低角膜应力并促进应力均匀分布，使其成为影响佩戴者舒适度和安全性的最关键因素。虽然基弧和直径的变化主要影响接触面积，但它们对应力分布的影响最小。本研究为改进隐形眼镜设计和提高隐形眼镜佩戴者的安全性提供了见解。
