Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain.
Graefes Arch Clin Exp Ophthalmol. 2024 Sep;262(9):2751-2764. doi: 10.1007/s00417-024-06400-5. Epub 2024 Mar 2.
This review explores mathematical models, blinking characterization, and non-invasive techniques to enhance understanding and refine clinical interventions for ocular conditions, particularly for contact lens wear.
The review evaluates mathematical models in tear film dynamics and their limitations, discusses contact lens wear models, and highlights computational mechanical models. It also explores computational techniques, customization of models based on individual blinking dynamics, and non-invasive diagnostic tools like high-speed cameras and advanced imaging technologies.
Mathematical models provide insights into tear film dynamics but face challenges due to simplifications. Contact lens wear models reveal complex ocular physiology and design aspects, aiding in lens development. Computational mechanical models explore eye biomechanics, often integrating tear film dynamics into a Multiphysics framework. While different computational techniques have their advantages and disadvantages, non-invasive tools like OCT and thermal imaging play a crucial role in customizing these Multiphysics models, particularly for contact lens wearers.
Recent advancements in mathematical modeling and non-invasive tools have revolutionized ocular health research, enabling personalized approaches. The review underscores the importance of interdisciplinary exploration in the Multiphysics approach involving tear film dynamics and biomechanics for contact lens wearers, promoting advancements in eye care and broader ocular health research.
本综述探讨了数学模型、眨眼特征描述以及非侵入性技术,以增进对眼部疾病(尤其是隐形眼镜佩戴者的眼部疾病)的理解,并改进临床干预措施。
本综述评估了泪膜动力学中的数学模型及其局限性,讨论了隐形眼镜佩戴者的模型,并强调了计算力学模型。还探讨了计算技术,基于个体眨眼动力学的模型定制,以及高分辨率相机和先进成像技术等非侵入性诊断工具。
数学模型为泪膜动力学提供了深入了解,但由于简化而面临挑战。隐形眼镜佩戴模型揭示了复杂的眼部生理学和设计方面,有助于镜片的开发。计算力学模型探索了眼球生物力学,通常将泪膜动力学纳入多物理场框架中。虽然不同的计算技术各有优缺点,但非侵入性工具,如光学相干断层扫描和热成像,在定制这些多物理场模型方面发挥着至关重要的作用,特别是对于隐形眼镜佩戴者。
最近在数学建模和非侵入性工具方面的进展彻底改变了眼部健康研究,实现了个性化方法。本综述强调了在涉及泪膜动力学和生物力学的多物理场方法中进行跨学科探索的重要性,这对眼保健和更广泛的眼部健康研究的进展至关重要。