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评估ACTLINK血浆治疗促进牙种植体骨整合和骨再生的安全性和有效性的前瞻性随机对照临床试验。

Prospective Randomized Controlled Clinical Trial to Evaluate the Safety and Efficacy of ACTLINK Plasma Treatment for Promoting Osseointegration and Bone Regeneration in Dental Implants.

作者信息

Kwon Jin-Seon, Cho Won-Tak, Lee Jong-Ho, Joo Ji-Young, Lee Jae-Yeol, Lim Youbong, Jeon Hyun-Jeong, Huh Jung-Bo

机构信息

Department of Prosthodontics, School of Dentistry, Pusan National University, Yangsan 50612, Republic of Korea.

Department of Prosthodontics, Dental Research Institute, Dental and Life Sciences Institute, Education and Research Team for Life Science on Dentistry, School of Dentistry, Pusan National University, Yangsan 50612, Republic of Korea.

出版信息

Bioengineering (Basel). 2024 Sep 29;11(10):980. doi: 10.3390/bioengineering11100980.

DOI:10.3390/bioengineering11100980
PMID:39451356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11505162/
Abstract

Recent studies have explored surface treatments, such as increasing the hydrophilicity of implant fixtures, to enhance the osseointegration of implants. This prospective clinical study aimed to assess the clinical stability and efficacy of plasma treatment applied to implants with sandblast-acid etching (SLA) surfaces before placement. Twenty-eight patients requiring implant placement provided consent and were assigned randomly to either the SLA group without plasma treatment or the SLA/plasma group with plasma treatment. Recall checks were conducted one and three months after the first-stage surgery, followed by a second surgery at four months. Although no significant differences in buccal bone defects or implant stability were observed between the groups, the SLA/plasma group showed significant increases in marginal bone changes on the mesial and distal sides, as assessed using periapical radiographs. This study underscores the potential of pre-implantation plasma treatment to enhance bone regeneration around implants.

摘要

最近的研究探索了表面处理方法，如增加种植体基台的亲水性，以增强种植体的骨整合。这项前瞻性临床研究旨在评估在种植体植入前对具有喷砂酸蚀（SLA）表面的种植体进行等离子体处理的临床稳定性和效果。28名需要植入种植体的患者签署了知情同意书，并被随机分配到未进行等离子体处理的SLA组或进行了等离子体处理的SLA/等离子体组。在一期手术后1个月和3个月进行复查，4个月时进行二期手术。尽管两组之间在颊侧骨缺损或种植体稳定性方面未观察到显著差异，但使用根尖片评估时，SLA/等离子体组在近中侧和远中侧的边缘骨变化有显著增加。这项研究强调了植入前等离子体处理在增强种植体周围骨再生方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/7bbf84a89f75/bioengineering-11-00980-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/7bbf84a89f75/bioengineering-11-00980-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/38ef2a69f575/bioengineering-11-00980-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/d150826f749c/bioengineering-11-00980-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/db84babc76b5/bioengineering-11-00980-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/99de9e31fdfa/bioengineering-11-00980-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/367495d098e6/bioengineering-11-00980-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/25a247ebb78e/bioengineering-11-00980-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/944e/11505162/7bbf84a89f75/bioengineering-11-00980-g013.jpg

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Early marginal bone loss around dental implants to define success in implant dentistry: A retrospective study.种植体周围早期边缘骨丧失对种植体牙科成功的定义：一项回顾性研究。
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