Ferrara A, Atakent Y
Med Care. 1986 Feb;24(2):179-87.
A reduction in newborn (NB) mortality is contingent on efforts of NB stabilization. The authors attempted to quantify stabilization into a score, the neonatal stabilization score (NSS) that correlates with outcome. The population for the study comprised 192 transported NBs who weighed less than 1,000 g at birth moved from level 1 hospitals in New York City during 5 years, 1977-1981. The NSS score was based on five components: vital signs, laboratory investigations, respiratory support, I.V. fluid administration, and specific managements. Each was rated 0, 1, or 2. A maximum score of 10 indicated excellent stabilization. Analyses for the validity and reliability of the NSS included the Mantel-Haenszel test (which controlled for birth weight and Apgar) and measurement of interrater agreement "k" (kappa statistic). Mortality rates were lower in those with higher NSS and odds of death were 2.39 times greater in NB with low NSS (chi 2 = 5.16; P less than 0.025). The calculated index of agreement k on 16 charts represented an excellent agreement beyond chance (k = 0.76, P less than 0.01).
新生儿死亡率的降低取决于新生儿稳定治疗的成效。作者试图将稳定治疗量化为一个评分,即与预后相关的新生儿稳定评分(NSS)。该研究的对象包括192例出生体重小于1000克的转运新生儿,这些新生儿于1977年至1981年的5年间从纽约市的一级医院转出。NSS评分基于五个方面:生命体征、实验室检查、呼吸支持、静脉输液及特殊处理。每个方面的评分为0、1或2分。最高分为10分,表示稳定治疗效果极佳。对NSS有效性和可靠性的分析包括Mantel-Haenszel检验(该检验控制了出生体重和阿氏评分)以及评价评分者间一致性的“k”值(kappa统计量)。NSS较高的新生儿死亡率较低,NSS较低的新生儿死亡几率高2.39倍(卡方 = 5.16;P < 0.025)。对16份病历计算得出的一致性指数k表明,一致性极佳,并非偶然(k = 0.76,P < 0.01)。