Zhang Ruyi, Li Qiling, Gu Yuxuan, Liao Wenli
School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Basic Medical School, Hubei University of Science and Technology, Xianning 437100, China.
Biology (Basel). 2024 Sep 28;13(10):779. doi: 10.3390/biology13100779.
The global rise in obesity rates has prompted a thorough evaluation of dietary strategies that may alleviate this metabolic issue. Fermented tea, a beverage rich in polyphenols and catechins, has emerged as a viable therapeutic option for obesity management. This review discusses the role of fermented tea in modulating the gut microbiome, a critical factor in energy regulation and obesity. We explore how the bioactive components in fermented tea influence gut health and their implications for metabolic health. Fermented tea may inhibit weight gain and fat accumulation in obese animal models, likely by promoting beneficial bacteria and suppressing harmful species. Changes in the production of short-chain fatty acids and improvements in gut barrier integrity are linked to enhanced insulin sensitivity and reduced inflammatory markers, essential for effective obesity management. However, barriers remain in applying these findings in clinical settings, such as the need for standardized fermentation techniques and accurate dosage assessments. This review underscores the therapeutic potential of fermented tea in obesity treatment and advocates for further research to enhance its integration with public health initiatives.
全球肥胖率的上升促使人们对可能缓解这一代谢问题的饮食策略进行全面评估。发酵茶是一种富含多酚和儿茶素的饮品，已成为肥胖管理的一种可行治疗选择。本综述讨论了发酵茶在调节肠道微生物群中的作用，肠道微生物群是能量调节和肥胖的关键因素。我们探讨了发酵茶中的生物活性成分如何影响肠道健康及其对代谢健康的影响。发酵茶可能通过促进有益菌和抑制有害菌来抑制肥胖动物模型中的体重增加和脂肪堆积。短链脂肪酸产生的变化和肠道屏障完整性的改善与胰岛素敏感性增强和炎症标志物减少有关，这对有效管理肥胖至关重要。然而，将这些发现应用于临床仍存在障碍，比如需要标准化发酵技术和准确剂量评估。本综述强调了发酵茶在肥胖治疗中的治疗潜力，并主张进一步开展研究，以加强其与公共卫生倡议相结合。
