器械辅助左心耳封堵：从基础科学到临床应用
Device-Assisted Left Atrial Appendage Exclusion: From Basic Sciences to Clinical Applications.
作者信息
Karpierz Julia Izabela, Piotrowski Michał, Bartuś Krzysztof, Chmiel Radosław, Wijatkowska Katarzyna, Słomka Artur
机构信息
CAROL-Cardiothoracic Anatomy Research Operative Lab, Department of Cardiovascular Surgery and Transplantology, Institute of Cardiology, Jagiellonian University Medical College, 31-008 Krakow, Poland.
Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
出版信息
J Cardiovasc Dev Dis. 2024 Oct 18;11(10):332. doi: 10.3390/jcdd11100332.
Device-assisted left atrial appendage exclusion plays a crucial role in the prevention of fatal ischemic complications in patients with atrial fibrillation and contraindications to anticoagulation treatment. Various devices with different safety profiles and device-related complications are available in daily practice to perform this procedure. In this review, the anatomy, physiology, and functions of the left atrial appendage were detailed, and all available devices used for epicardial and endocardial exclusion of the left atrial appendage and their clinical outcomes were discussed. Future research should aim to further investigate the long-term effects of left atrial appendage exclusion on body homeostasis, blood coagulation, and cardiac function.
器械辅助左心耳封堵在预防房颤且有抗凝治疗禁忌证患者的致命性缺血并发症中发挥着关键作用。日常实践中有各种具有不同安全性特征和器械相关并发症的器械可用于实施该手术。在本综述中，详细阐述了左心耳的解剖、生理和功能，并讨论了用于心外膜和心内膜左心耳封堵的所有可用器械及其临床结果。未来的研究应旨在进一步探究左心耳封堵对身体内环境稳定、血液凝固和心脏功能的长期影响。
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