Kiselev Roman, Zheravin Aleksander
Meshalkin National Medical Research Centre, Novosibirsk 630055, Russia.
J Pers Med. 2024 Sep 26;14(10):1024. doi: 10.3390/jpm14101024.
: The choice of prosthesis for vertebral body reconstruction (VBR) remains a controversial issue due to the lack of a reliable solution. The subsidence rate of the most commonly used titanium mesh cages (TMC) ranges from 42.5% to 79.7%. This problem is primarily caused by the differences in the elastic modulus between the TMC and bone. This review aims to summarize the clinical and radiological outcomes of new 3D-printed artificial vertebral bodies (3DP AVB). : A literature search of PubMed, Scopus and Google Scholar was conducted to extract relevant studies. After screening the titles and abstracts, a total of 50 articles were selected for full-text analysis. : Preliminary data suggest fewer implant-related complications with 3DP AVB. Most comparative studies indicate significantly lower subsidence rates, reduced operation times and decreased intraoperative blood loss. However, the scarcity of randomized clinical trials and the high variability of the results warrant caution. : Most literature data show an advantage of 3DP AVB in terms of the operation time, intraoperative blood loss and subsidence rate. However, long manufacturing times, high costs and regulatory issues are this technology's main drawbacks.
由于缺乏可靠的解决方案，椎体重建（VBR）假体的选择仍然是一个有争议的问题。最常用的钛网笼（TMC）的下沉率在42.5%至79.7%之间。这个问题主要是由TMC和骨骼之间的弹性模量差异引起的。本综述旨在总结新型3D打印人工椎体（3DP AVB）的临床和放射学结果。：对PubMed、Scopus和谷歌学术进行文献检索，以提取相关研究。在筛选标题和摘要后，共选择了50篇文章进行全文分析。：初步数据表明，3DP AVB植入相关并发症较少。大多数比较研究表明，下沉率显著降低，手术时间缩短，术中出血量减少。然而，随机临床试验的稀缺性和结果的高度变异性值得谨慎对待。：大多数文献数据显示，3DP AVB在手术时间、术中出血量和下沉率方面具有优势。然而，制造时间长、成本高和监管问题是这项技术的主要缺点。
