Alexandersson Hanna, Dehlin Mats, Jin Tao
Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 41346 Gothenburg, Sweden.
Department of Rheumatology, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.
Pathogens. 2024 Oct 11;13(10):891. doi: 10.3390/pathogens13100891.
This study aimed to determine the incidence of septic arthritis across adult age groups in Västra Götaland Region (VGR) of Sweden, while also comparing disease characteristics among different age groups with hematogenous septic arthritis.
Using ICD-10 codes for septic arthritis from 2016 to 2019, we identified 955 patients in VGR. We reviewed the medical records of 216 adult patients with hematogenous septic arthritis and compared data across age groups.
The overall incidence of septic arthritis in adults was 4 per 100,000 persons annually, rising to 14 per 100,000 in those ≥80 years. The median age of the 216 patients was 71. The comparison across age groups (18-64, 65-79, and ≥80) showed significantly longer hospital stays and higher mortality rate in the older groups. CRP levels were higher in the middle age group, SF-WBC counts were lower in the youngest age group, and synovial fluid crystals were more common in the oldest. No differences were found in joint involvement or the organisms isolated.
The incidence of septic arthritis is 6.5 times higher in patients aged ≥ 80 compared to those under 65, highlighting the need to consider age-related differences in disease management.
本研究旨在确定瑞典韦斯特罗斯-哥德堡地区(VGR)成年各年龄组感染性关节炎的发病率,同时比较不同年龄组血源性感染性关节炎的疾病特征。
利用2016年至2019年感染性关节炎的国际疾病分类第十版(ICD-10)编码,我们在VGR地区识别出955例患者。我们回顾了216例成年血源性感染性关节炎患者的病历,并比较了各年龄组的数据。
成年人感染性关节炎的总体发病率为每年每10万人中有4例,80岁及以上人群中这一发病率升至每10万人中有14例。216例患者的中位年龄为71岁。各年龄组(18 - 64岁、65 - 79岁和80岁及以上)的比较显示,年龄较大的组住院时间明显更长,死亡率更高。中年组的C反应蛋白(CRP)水平较高,最年轻年龄组的滑液白细胞(SF-WBC)计数较低,最年长组的滑液晶体更为常见。在关节受累情况或分离出的病原体方面未发现差异。
80岁及以上患者的感染性关节炎发病率比65岁以下患者高6.5倍,这突出表明在疾病管理中需要考虑与年龄相关的差异。