通过电子显微镜断层扫描建立的特定前信使核糖核蛋白颗粒的三维结构。
Three-dimensional structure of a specific pre-messenger RNP particle established by electron microscope tomography.
作者信息
Skoglund U, Andersson K, Strandberg B, Daneholt B
出版信息
Nature. 1986;319(6054):560-4. doi: 10.1038/319560a0.
DOI:10.1038/319560a0
PMID:3945344
Abstract
Electron microscope tomography has been used to refine the structural analysis of individual RNP particles synthesized on Balbiani ring genes in Chironomus tentans. The spherical particles have a diameter of 500 A and are composed of a thick RNP ribbon bent into an asymmetrical, four-domain, ring-like configuration. The first domain, containing the 5' end of the transcript, and the fourth domain, containing the 3' end, are close to each other.
摘要
电子显微镜断层扫描技术已被用于完善对在摇蚊唾腺染色体巴尔比亚尼环基因上合成的单个核糖核蛋白（RNP）颗粒的结构分析。这些球形颗粒直径为500埃，由一条粗的核糖核蛋白带组成，该带弯曲成不对称的四结构域环状构型。包含转录本5'端的第一个结构域和包含3'端的第四个结构域彼此靠近。
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