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为什么侵入性脑刺激有时能改善记忆,有时却会损害记忆?

Why does invasive brain stimulation sometimes improve memory and sometimes impair it?

作者信息

Mohan Uma R, Jacobs Joshua

机构信息

Surgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, Maryland, United States of America.

Department of Biomedical Engineering, Columbia University, New York City, New York, United States of America.

出版信息

PLoS Biol. 2024 Oct 25;22(10):e3002894. doi: 10.1371/journal.pbio.3002894. eCollection 2024 Oct.

Abstract

Invasive brain stimulation is used to treat individuals with episodic memory loss; however, studies to date report both enhancement and impairment of memory. This Essay discusses the sources of this variability, and suggests a path towards developing customized stimulation protocols for more consistent memory enhancement.

摘要

侵入性脑刺激被用于治疗患有发作性记忆丧失的个体;然而,迄今为止的研究报告了记忆的增强和损害。本文讨论了这种变异性的来源,并提出了一条开发定制刺激方案以更一致地增强记忆的途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38fa/11616832/d46220c5a61c/pbio.3002894.g001.jpg

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