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荟萃分析:腰方肌前阻滞在腹部手术中的应用

Meta-analysis: The utility of the anterior quadratus lumborum block in abdominal surgery.

作者信息

Evans Brogan G A, Ihnat Jacqueline M H, Zhao K Lynn, Kim Leah, Pierson Doris, Yu Catherine T, Lin Hung-Mo, Li Jinlei, Golshan Mehra, Ayyala Haripriya S

机构信息

Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.

Division of Surgical Oncology, Department of Surgery, Yale School of Medicine, New Haven, CT, USA.

出版信息

Am J Surg. 2025 Jan;239:116014. doi: 10.1016/j.amjsurg.2024.116014. Epub 2024 Oct 18.

Abstract

BACKGROUND

Regional anesthesia is routinely used in Enhanced Recovery After Surgery pathways to improve post-operative recovery times. No consensus has been reached on optimal block type. This study reviews the current literature as it pertains to the anterior quadratus lumborum (aQL) block in all abdominal surgeries, as well as its efficacy compared to the transversus abdominis plane (TAP) block.

METHODS

PubMed was searched for original, peer-reviewed articles that include "(anterior) quadratus lumborum block." 89 articles were included. Data was extracted according to PRISMA guidelines, with articles manually reviewed by two independent reviewers. A meta-analysis was then conducted on a subset of 14 randomized control trials (RCT) evaluating total oral morphine equivalent consumed at 12 and 24 ​h post-operatively in patients who received an aQL block compared to control.

RESULTS

28 articles were included with 14 RCT used in a random-effects meta-analysis. There was a significant reduction in post-operative pain scores and opioid use in patients who receive an aQL block for abdominal surgeries. Meta-analysis determined a decrease in total oral morphine equivalent consumed at both 12 and 24 ​h post-operatively compared to controls. Compared to no region block, both the aQL and TAP block show a significant reduction in pain and post-operative opioid consumption.

CONCLUSION

The literature demonstrates non-inferiority of the aQL block compared to the TAP block in abdominal surgery, with some studies suggesting its superiority. Limitations include heterogeneity in study type and design, as well as the presence of confounding variables when comparing across surgery types.

摘要

背景

区域麻醉在术后加速康复路径中常规使用,以缩短术后恢复时间。对于最佳阻滞类型尚未达成共识。本研究回顾了当前与所有腹部手术中腰方肌前肌(aQL)阻滞相关的文献,以及与腹横肌平面(TAP)阻滞相比的疗效。

方法

在PubMed上搜索原始的、经过同行评审的文章,其中包括“(前)腰方肌阻滞”。共纳入89篇文章。根据PRISMA指南提取数据,由两名独立评审员对文章进行人工评审。然后对14项随机对照试验(RCT)的子集进行荟萃分析,评估接受aQL阻滞的患者与对照组相比术后12小时和24小时消耗的口服吗啡总量。

结果

纳入28篇文章,14项RCT用于随机效应荟萃分析。接受aQL阻滞进行腹部手术的患者术后疼痛评分和阿片类药物使用量显著降低。荟萃分析确定,与对照组相比,术后12小时和24小时口服吗啡总量均有所减少。与未进行区域阻滞相比,aQL阻滞和TAP阻滞均显示疼痛和术后阿片类药物消耗量显著降低。

结论

文献表明,在腹部手术中,aQL阻滞与TAP阻滞相比具有非劣效性,一些研究表明其具有优越性。局限性包括研究类型和设计的异质性,以及在比较不同手术类型时存在混杂变量。

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