Department of Restorative Dentistry, Faculty of Dentistry, Mugla Sitki Kocman University, Mugla, Turkey.
Department of Pedodontics, Faculty of Dentistry, Mugla Sitki Kocman University, Mugla, Turkey.
BMC Oral Health. 2024 Oct 25;24(1):1286. doi: 10.1186/s12903-024-05057-0.
The frequent occurrence of dental caries and periodontal diseases in women during pregnancy may be due to many factors, such as salivary variables. The aim of this study was to evaluate the effects of pregnancy on salivary pH, flow rate, the DMFT index, and CPI sores.
A total of 198 volunteers (pregnant in different trimesters and non- pregnant) were included for the present observational cross-sectional study. Data about sociodemographic characteristics and dental and systemic health conditions were recorded. Unstimulated saliva samples were collected for 5 min via the spitting method. The pH of the saliva was measured by a portable pH meter. The salivary flow rate was determined by the weight measurement method. The DMFT index and CPI were determined. The statistical evaluation was performed using Robust ve Poisson Regression analyses (p < 0.05).
It was determined that there was a gradually significant decrease in the Ph value from the first trimester to the third trimester during pregnancy, which was lower than the control group. (p < 0.001) The flow rate of pregnants in their third trimester was lower than that of first trimester (p = 0.017). The CPI scores of pregnant women were significantly greater than that of non-pregnants (p = 0.042), while the DMFTs were similar among all groups.
Our findings indicate that pregnancy leads to a notable reduction in unstimulated salivary pH and flow rate, which also has a detrimental impact on periodontal health.
Clinical Trials-ID: NCT06343337; Registration Date: 04.01.2024.
孕妇频繁发生的龋齿和牙周疾病可能与唾液变量等多种因素有关。本研究旨在评估妊娠对唾液 pH 值、流率、DMFT 指数和 CPI 评分的影响。
本观察性横断面研究共纳入 198 名志愿者(处于不同妊娠阶段的孕妇和非孕妇)。记录了社会人口统计学特征以及口腔和全身健康状况的数据。采用自然分泌法收集 5 分钟的非刺激性唾液样本,使用便携式 pH 计测量唾液 pH 值,通过称重法测量唾液流率,同时还测定了 DMFT 指数和 CPI。采用稳健 ve 泊松回归分析进行统计评估(p<0.05)。
研究结果表明,妊娠期间唾液 pH 值从第一孕期逐渐显著下降至第三孕期,低于对照组(p<0.001)。妊娠第三孕期的唾液流率低于第一孕期(p=0.017)。孕妇的 CPI 评分显著高于非孕妇(p=0.042),而所有组之间的 DMFTs 相似。
我们的研究结果表明,妊娠会导致唾液 pH 值和流率明显降低,这对牙周健康也有不利影响。
临床试验-ID:NCT06343337;注册日期:2024 年 01 月 04 日。