Bioaccessibility and Antidiabetic Potential of and Fruits in a Simulated Gastrointestinal Tract Model.

This study evaluated the influence of gastrointestinal digestion on the bioaccessibility and antidiabetic potential of () and () fruits. After digestion, the content of total phenolics and flavonoids reduced by 58.3 and 73.51% in and 48.33 and 88.43% in . In addition, compounds such as rutin, ρ-coumaric acid, catechin and epicatechin reduced during digestion for both fruits. The antioxidant potential by the ABTS assay increased by 153.3% for and 273.46% for in the intestinal phase. However, using the ORAC assay, the antioxidant potential of reduced from 255.42 to 112.17 μmol TE g. The capacity of fruit to reduce α-amylase activity reduced 23.71-fold after digestion, but the potential to inhibit α-glucosidase increased 17.8-fold. The antiglycation potential reduced in both fruits after the in vitro gastrointestinal digestion. Thus, the bioaccessibility of the phenolic compounds from the fruits, as well as their functional potential, were influenced by the digestive process, as well as by the sample evaluated.