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硒及其补充剂对癌症发生的有益影响,以及纳米硒在恶性肿瘤治疗中的应用。

Beneficial Effects of Selenium and Its Supplementation on Carcinogenesis and the Use of Nanoselenium in the Treatment of Malignant Tumors.

机构信息

Department of Medical Pathomorphology, Medical University of Białystok, 15-269 Białystok, Poland.

出版信息

Int J Mol Sci. 2024 Oct 20;25(20):11285. doi: 10.3390/ijms252011285.

Abstract

Selenium was recognized as a non-toxic element in the second half of the 20th century. Since then, the positive impact of selenium on the functioning of the human body has been noticed. It has been shown that low levels of selenium in the body are significantly associated with a higher risk of developing cancer. Selenium acts as an antioxidant and inhibits the proliferation of cancer cells. It has been shown that selenium supplementation may contribute to reducing the risk of DNA mutations and carcinogenesis. Nanomedicine has become very helpful in both the diagnosis and treatment of cancer. Due to its anticancer properties, selenium is used in nanotechnology as selenium nanoparticles.

摘要

硒在 20 世纪后半叶被确认为一种无毒元素。从那时起,人们注意到硒对人体功能的积极影响。研究表明,体内硒含量低与癌症风险增加显著相关。硒作为一种抗氧化剂,能抑制癌细胞的增殖。研究表明,硒的补充可能有助于降低 DNA 突变和致癌的风险。纳米医学在癌症的诊断和治疗中都非常有帮助。由于其抗癌特性,硒在纳米技术中被用作硒纳米粒子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd42/11508626/7a66088818a5/ijms-25-11285-g001.jpg

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