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住院儿科患者中新冠病毒病的严重程度概况

Severity Profile of COVID-19 in Hospitalized Pediatric Patients.

作者信息

Costa Vânia Chagas da, Montarroyos Ulisses Ramos, Lopes Katiuscia Araújo de Miranda, Santos Ana Célia Oliveira Dos

机构信息

Postgraduate Program in Health Sciences, Universidade de Pernambuco, Recife 50100-010, Pernambuco, Brazil.

School of Nursing Our Lady of Grace, Universidade de Pernambuco, Recife 50100-010, Pernambuco, Brazil.

出版信息

Children (Basel). 2024 Oct 16;11(10):1249. doi: 10.3390/children11101249.

Abstract

OBJECTIVE

We aimed to describe the clinical characteristics associated with severity in children hospitalized with COVID-19.

METHOD

This was an epidemiological cohort study conducted in two hospitals, one of which was a reference center for the treatment of COVID-19 cases. Data were collected from the reports generated by the hospital epidemiology centers and the medical records of patients aged between 0 and 14 years with a diagnosis of COVID-19, hospitalized between March 2020 and June 2021. To analyze the association between the clinical profile and severity, the cases were classified as severe (severe and critical) and non-severe (asymptomatic, mild, and moderate).

RESULTS

Of the 191 children followed up in the cohort, 73.3% developed the severe form. The percentage of children with oxygen saturation below 95% was 46.6%. In the multivariate analysis, a higher risk of severity was estimated among children with uncontrolled asthma (RR = 13.2), who were overweight or obese (RR = 3.21), who had cough symptoms (RR = 2.72), and those aged under one year (RR = 3.23).

CONCLUSIONS

This result underscores the need to improve healthcare at every level for children and for the management of asthma and nutrition when considering children with this clinical profile who are diagnosed with COVID-19.

摘要

目的

我们旨在描述新冠病毒病(COVID-19)住院儿童中与病情严重程度相关的临床特征。

方法

这是一项在两家医院开展的流行病学队列研究,其中一家是COVID-19病例治疗参考中心。数据收集自医院流行病学中心生成的报告以及2020年3月至2021年6月期间住院的0至14岁确诊为COVID-19的患者的病历。为分析临床特征与病情严重程度之间的关联,病例被分为重症(重症和危重症)和非重症(无症状、轻症和中症)。

结果

在该队列中随访的191名儿童中,73.3%发展为重症。血氧饱和度低于95%的儿童比例为46.6%。在多变量分析中,未控制哮喘的儿童(相对危险度=13.2)、超重或肥胖的儿童(相对危险度=3.21)、有咳嗽症状的儿童(相对危险度=2.72)以及1岁以下的儿童(相对危险度=3.23)病情严重的风险更高。

结论

这一结果强调,对于具有此临床特征且被诊断为COVID-19的儿童,需要在各个层面改善医疗保健,并加强哮喘和营养管理。

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